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cerebellopontine angle tumors

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cerebellopontine angle tumors

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    1. Cerebellopontine Angle Tumors John K. Yoo, M.D. Jeffrey T. Vrabec, M.D. May 7, 1997

    3. History Unilateral sensorineural hearing loss Sudden sensorineural hearing loss Unilateral tinnitus Vestibular symptoms Facial hypesthesia and weakness Diplopia Hoarseness, dysphagia, aspiration

    4. Physical Examination Thorough cranial nerve exam Extra-ocular movements Funduscopic exam Facial motor and sensory function Pneumatic otoscopy/Weber/Rinne Hitselberger’s sign Gag/TVC/SCM and trapezius

    5. Diagnostic Tests Pure tone and speech discrimination audiometry Rollover Impedance audiometry acoustic reflex tone decay Auditory brainstem evoked response (ABR) Vestibular testing (ENG)

    6. Radiographic Studies CT MRI

    7. Acoustic Neuroma Benign slow growing tumors from Schwann cells surrounding CN VIII 10% of the intracranial tumors and >90% of the CPA tumors Incidence 0.1 to 2.5 per 100,000 Associated with neurofibromatosis Rate of growth 0.2 to 4.0 mm per year

    8. Acoustic NeuromaRadiographic Image Centered on IAC, spherical, enlarge the medial IAC, acute bone-tumor angle CT: isodense and enhances with contrast Inhomogeneous due to cystic degeneration or intratumoral hemorraging MRI: isointense or hypointense on T1 and T2, but becomes markedly enhanced on T1-gadolinium

    9. Acoustic NeuromaRationale of Management Observation Surgery for small intracanalicular tumors Surgery for medium-sized tumors (1-3 cm) Surgery for only-hearing ear Surgery for bilateral acoustic neuromas (Neurofibromatosis-type II)

    10. Meningiomas 15% of intracranial tumors and 3% of CPA tumors Arise from cells lining the arachnoid villa Benign and do not metastasize, but locally aggressive because they invade bone Signs and symptoms referable to site of involvement

    11. MeningiomaRadiographic Image Eccentric to IAC hyperostosis at medial IAC Hemispherical and sessile with obtuse bone-tumor angle CT: hypodense with calcification with marked enhancement; homogeneous MRI: isointense/hypointense on T1, but only moderate enhancement on T1-gad

    12. Meningiomas Several histologic subtypes syncytial transitional fibrous angioblastic sarcomatous Surgical excision with removal of underlying bone

    13. Hemangioma Hamartomatous vascular malformations Arise from geniculate ganglion or at the IAC Closely associated with the facial nerve MRI: hyperintense on T2 CT: intratumoral bone spicules and “honeycomb” pattern of surrounding bone Treatment is surgical excision

    14. Other CPA lesions Facial nerve schwannoma Cholesteatoma (epidermoid) Lipoma Arachnoid cyst

    15. Translabyrinthine Advantages No retraction of cerebellum Allows good identification of CN VII Allows good exposure of IAC Less risk of CSF leak Disadvantages Hearing is sacrificed Technique

    16. Middle Fossa Approach Advantages Excellent for intracanalicular tumors, especially at the lateral end of the IAC Hearing preservation is possible Extradural with low risk of CSF leak Disadvantages Lack of access to CPA and posterior fossa Need to retract temporal lobe Technique

    17. Retrosigmoid/SuboccipitalApproach Advantages Hearing preservation is possible Access to CPA Disadvantages Limited access to lateral IAC/Fundus Difficult to repairing or grafting CN VII Increased risk of air embolism/CSF leak/ post-op headache Cerebellar retraction is necessary Technique

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