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胚胎學

胚胎學. 陳建榮. http://web.nchu.edu.tw/pweb/users/chenjr/. 教科書及參考資料： 1. The Developing Human (9TH, 2013, by Keith L. Moore & T. V. N. Persaud) 2. Langman’s medical embryology (12th, 2012, by T.W. Sadler) 3. Veterinary embryology (2006, by McGeady et al.)

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胚胎學

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  1. 胚胎學 陳建榮 http://web.nchu.edu.tw/pweb/users/chenjr/

  2. 教科書及參考資料： 1. The Developing Human (9TH, 2013, by Keith L. Moore & T. V. N. Persaud) 2. Langman’s medical embryology (12th, 2012, by T.W. Sadler) 3. Veterinary embryology (2006, by McGeady et al.) 4. Domestic animal embryology (2010, by Hyttel et al.) 5. http://embryology.med.unsw.edu.au/ 6. 講義 評量方式： 期中考 (45%) 期末考 (45%) 平時成積 (10%)

  3. Topics • 配子的形成與受精 • 受精卵的著床與胚胎成形 • 各系統的正常或異常發育與臨床疾病的關係 • 畸胎學

  4. Embryology • Animal development is a continuous process that begins when a zygote is formed • Development does not stop at birth

  5. Developmental Periods • Gametogenesis • Spermatogenesis • Oogenesis • Prenatal period (Fertilization) • Embryo: Zygote • Cleavage • Implantation • Gastrulation… • Organogenesis • Fetus • Postnatal period • Neonate (<1 month) • Infancy (< 1 yr) • Childhood • Puberty (13 yr – 16 yr) • Adulthood

  6. LNMP (last normal menstrual period) 胎齡: fetus embryo Trimester

  7. Carnegie stagesare a system used by embryologists to describe the apparent maturity of embryos 1st trimester

  8. 1st week

  9. Formation of Bilaminar Embryonic Disc Stage 5: 7th –12th day full implantation 2nd week

  10. Stages 6-9: Day 13-21 Somites 3rd week

  11. Stages 10-17 4th to 6th week

  12. 7 8 • Embryo(end of the 8th week) - all major structures are present • Fetus(after 8th week)

  13. Genetics and Molecular biology are applied in human development • Ian Wilmut [1997] Somatic cell nuclear transfer – Dolly lamb • Embryonic stem cell

  14. Somatic cell nuclear transfer 桃莉羊與Ian Wilmut教授

  15. 複製動物的肉和乳品安全嗎？ 基因改良食品的安全性？

  16. 複製人類是否無可避免？聯合國管理下的未來選擇

  17. Stem cell Embryonic stem cell Morula Blastocyt 組織修補 \器官替換 人造器官(心臟、肺、支氣管…)

  18. 「救命寶寶」（rescue baby） 胚胎著床前基因診斷

  19. 全球首例 英允許「一父二母」基改寶寶 • Dysfunctional mitochondria: • Diabetes mellitus and deafness (DAD) • Visual loss • Seizures • Dementia …

  20. Anatomical position

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