Body fluid regulation abnormalities
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Body fluid Regulation & abnormalities. Lec 10. Distribution of total body water . Factors affecting total body water:. 1. gender 2. age 3. Total body fat. Body fluid compartments;. 1. intracellular (2/3) 2. Extracellular (1/3); A. Interstitial fluid B. Plasma. Daily input & output.

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Factors affecting total body water
Factors affecting total body water:

  • 1. gender

  • 2. age

  • 3. Total body fat


Body fluid compartments
Body fluid compartments;

  • 1. intracellular (2/3)

  • 2. Extracellular (1/3);

  • A. Interstitial fluid

  • B. Plasma



Regulation of fluid exchange between body compartments
Regulation of fluid exchange between body Compartments

ICF & ECF;

Determined by osmotic effect of solutes across the cell membrane.

Plasma & interstitial spaces

Colloid osmotic force & hydrostatic force across the capillary membrane.


Why its important to maintain body fluid in critically ill patients
Why its important to maintain body fluid in critically ill patients?

  • 1. Dehydration will lead to hypovolemia and renal impairment.

  • 2. Over-hydration will lead to pulmonary edema and heart failure.


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