MITOSIS. What is the cell cycle?. Growth And Division. What is Mitosis?. Nuclear Division. What is Chromatin ?. ( Thin Chroma tin ) Stretched out, unwound DNA Looks like spaghetti Not visible under microscope. What is a Chromosome?.
Stretched out, unwound DNA
Looks like spaghetti
Not visible under microscope
Coiled up (condensed) version of chromatin; easier for moving DNA
(Looks like a slinky)
Holds Sister Chromatids together
Where spindle fibers grab chromosome
(Think: Centro = center mere = middle)
Two identical strands of a chromosome
When cell gets bigger and makes lots of proteins
1st part of Interphase
Makes a copy of the DNA
Single strand →Double strand
2nd part of Interphase
“Growth 2” Phase
Cell is getting ready to divide
Getting organelles and proteins
(Like going to grocery store to get the food to prepare dinner)
3rd part of Interphase
Mitosis and Cytokinesis
longest phase of the Cell Cycle?
(NOT part of Mitosis)
Includes: G1, S, G2
“The Professional MetAna on the Telophone.”
Longest phase of Mitosis!!!
Spindle fibers (muscles of chromosome) form to help move
Chromosomes are lined up in the middle of the cell
Spindle fibers are attached and centrioles go to the poles
Chromosomes get pulled apart by spindle fibers
“The End” or “Tidy Up”
Uncoiling of chromosomes
Nuclear envelope reforms
Spindle fibers go “bye-bye”
This is the next stage after mitosis.
Actual cell division into two cells dividing into two daughter cells
What structure appears?
What structure appears?
Creates a CELL PLATE
(Think: Hard cell wall is like a hard plate)
Why do normal cells stop growing when they touch other cells or reach the sides of a petri dish?
Contact with other cells or the sides of the dish signal to the cell to stop growing.
This happens when you cut your finger. The cells grow rapidly to fill in the cut. When the cells touch, they go back to normal cell cycle.
Internal regulators are proteins that respond to events inside the cell .
External regulators are proteins that respond to events outside the cell.
What is it called when cells have lost their ability to control their growth?
Cells that have not differentiated yet.
Volume or Surface Area?
The bigger the cell gets the less efficient the cell is at doing its job (function) in the body.
What are haploid cells?
2 pairs of chromosomes
Somatic Cells = 23 pairs
1 set of chromosomes
Sex Cells = 23 single chromosomes