Psychoactive Drugs. Professor Lana Chase. Psychoactive Drug Categories. Anti-psychotics : Schizophrenia, Agitation Anti-depressants : Depression, OCD, Anxiety Mood Stabilizers : Bipolar Disorder Anti-Anxiety: Anxiety /Panic Disorders Psycho-stimulants : ADHD, Narcolepsy.
Professor Lana Chase
sedation, anticholinergic side effects
discontinue medication, Notify MD,
treat symptomatically: cooling blanket, Bromocriptine, cardiac meds if necessary.
Potentiates action of CNS Depressants:
e.g.. narcotics, alcohol
(Antagonist) benzodiazapine receptor blocker
** works best with people who never took benzo’s because they are accustomed to immediate effect.
Uses: panic disorder, depression, GAD, enuresis, sedation (for insomnia)
***2-4 weeks for antidepressant effect
4-9 mos tx or may be lifetime if depression recurrent
Anxiety Disorders: SSRI (Paxil) now treatment of choice
Selective Serotonin Reuptake Inhibitors
increases serotonin reuptake at receptor site
less SE than TCI’s
less anticholinergic, no wt. Gain, safer for cardiac pts.
& pregnant women
Signs and Symptoms
confusion , disorientation, mania, restlessness, diaphoresis, shivering, diarrhea, nausea.
D/C all serotonergic drugs including
SSRI’s, MAOI’s, anticonvulsants, Ativan, Klonapin
** do not reintroduce serotonin drugs
.5-1.5 meq./l therapuetic above 2 meq. toxic
Hold Lithium, Notify MD, get serum lithium level to confirm
instruct patient in S/S of toxicity
excessive sweating: will raise serum lithium levels (caution for people who have outdoor jobs in the heat (roofer)
contraindicated/caution with diuretics such as Hydrodiuril (HCTZ)