1 / 15

INTRODUCTION TO VIRUSES AND THEIR STRUCTURE:

INTRODUCTION TO VIRUSES AND THEIR STRUCTURE: . PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mail Web site. Objectives Students should be able to:.

sage
Download Presentation

INTRODUCTION TO VIRUSES AND THEIR STRUCTURE:

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. INTRODUCTION TO VIRUSES AND THEIR STRUCTURE: PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mailWeb site

  2. ObjectivesStudents should be able to: • Summarise virus properties and control. • Describe virus structure and enzymes in outline

  3. Introduction to virology

  4. How are virulent virus infections controlled?

  5. To associate a new virus with a disease it must be grown in pure culture and shown to be virulent.

  6. Virus structure

  7. The nucleic acid: Virus particles do not contain messenger RNA, this is in the host cell A virus will contain either an RNA or DNA genome

  8. The capsid protein The capsid proteins protects the nucleic acid. They are arranged into are 3 forms of symmetry, icosahedral, helical and complex.

  9. Icosahedral capsid An icosahedron has 12 vertices with 20 triangular sides, termed facets, like a geophysical dome. It is made of capsomeres, which appear spherical by em..

  10. Helical capsid

  11. Complex capsid

  12. Envelope

  13. Enzymesand regulatory proteins These are virus proteins which are essential to virus replication. Some are present in the virus particle, others are only in the host cell.

  14. Examples of non-structural enzymes found in the infected cell but not the virus :

  15. Summary • Viruses require living cells and are therefore infectious but can be contained by hygiene/vaccines. • Several hundred particles which look identical are made in each infected cell overnight. • Viruses comprise a nucleic acid surrounded by protein. Some have an additional envelope which makes them more fragile.

More Related