LECTURE 12:. Virus Genome Replication. Waqas Nasir Chaudhry. Viro100: Virology 3 Credit hours NUST Centre of Virology & Immunology. Transcription of virus genomes. There are four main categories of virus genome: dsDNA , ssDNA , dsRNA and ssRNA
carry out reverse transcription;
these viruses known as pararetroviruses and
Class VII was formed to accommodate them i.e. Badnavirus of plants
There are a few single stranded nucleic acids of viruses where there is a mixture of (+)and(−) polarity within the strand, in other words there are open reading frames (ORFs) in both directions.
Example Sendai Viruses
Increasing understanding of how viruses replicate their genomes necessitated some modiﬁcations to this dogma in 1970; many viruses have RNA genomes that are copied to RNA, and some viruses copy from RNA to DNA
Modiﬁcations to the central dogma