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Leukemia. Jeff Liu, Period 5. What Is Leukemia?. Cancer of the white blood cells Acute or Chronic Affects ability to produce normal blood cells Bone marrow makes abnormally large number of immature white blood cells called blasts. History. Means “white blood” in Greek

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Leukemia l.jpg

Leukemia

Jeff Liu, Period 5


What is leukemia l.jpg
What Is Leukemia?

  • Cancer of the white blood cells

  • Acute or Chronic

  • Affects ability to produce normal blood cells

  • Bone marrow makes abnormally large number of immature white blood cells called blasts


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History

  • Means “white blood” in Greek

  • Discovered by Dr. Alfred Velpeau in France, 1827

  • Named by pathologist Rudolf Virchow in Germany, 1845


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Main Types

  • Acute Lymphocytic Leukemia (ALL)

  • Acute Mylogenous Leukemia (AML)

  • Chronic Lymphocytic Leukemia (CLL)

  • Chronic Mylogenous Leukemia (CML)


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Demographics of Leukemia Patients (2001 Data)

CLL=Chronic Lymphocytic

ALL=Acute Lymphocytic

CML=Chronic Mylogenous

AML=Acute Mylogenous

Total Reported Cases = 31,500

Sources from Leukemia, Lyphoma, Myeloma Facts 2001


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Symptoms

  • When there are excessive white blood cells --> Infections

  • When there are few red blood cells: Paleness --> Anemia

  • When there are few platelets --> Excessive bleeding


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Tests For Diagnosis

  • Finger prick

  • Blood sample

  • Blood dye

  • Bone marrow sample

  • Spinal Tap/Lumbar Puncture


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Platelet

Platelet

White Cell

Red Cell

Red Cell

Blasts

White Cell

Normal human blood

Blood with leukemia

Pictures Of Blood

Sources from beyond2000.com

Sources from Arginine.umdnj.edu


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Effects On the Body

  • Attacks the immune system

  • Infections

  • Anemia

  • Weakness

  • No more regular white blood cells, red blood cells, and platelets

  • Blasts clog blood stream and bone marrow


Development of leukemia in the bloodstream l.jpg

Stage 1- Normal

Stage 2- Symptoms

Stage 3- Diagnosis

Stage 5a- Anemia

Stage 4- Worsening

Stage 5b- Infection

Development of Leukemia in the Bloodstream

Legend

White Cell

Red Cell

Platelet

Blast

Germ

Sources from Leukemia, by D. Newton and D. Siegel


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Causes

  • High level radiation/toxin exposure

  • Viruses

  • Genes

  • Chemicals

  • Mostly unknown

  • Can’t be caught


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Treatment

  • Chemotherapy

  • Immunotherapy

  • Radiation

  • Bone marrow transplant


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Research

  • New drugs

  • Cord blood and planceta


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TheEnd


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