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1. _____________________________________________ Donald Mair Commercialisation and Knowledge Exchange Team Biotechnology and Biological Sciences Research Council

2. The UK Spends a Lot on Science £8,932,000,000 UK Government Funded R&D 2005 - 06

3. Comparisons Police Secondary Schools NHS

4. UK Government Funded R&D 2005 - 2006 : £8,932m

5. Government Funding Increasing UK Science budget (£M) • Ten year science and innovation framework - promise year-on-year increase • Current budget - 5.4% on average increase - above inflation

6. All Governments Value Science “Britain has an enviable record of scientific achievement and invention. No other country has a list of firsts like ours. As scientists and inventors the British are still amongst the best.” “The strength and creativity of our science base is a key national asset as we move into the 21st century.” “The new Britain will be built on skills, science and enterprise - backing the scientist and inventor, rewarding the entrepreneur, challenging all of us to improve our skills”

7. All Governments Value Science “The challenge that faces us is the reinvention of our economy according to new principles. Science, maths, engineering and technology must be at the heart of that project. We must rebalance our economy so that manufacturing and research are as valued as finance and consumer services.” “It is absolutely vital that the UK develops and builds on its outstanding record in science and engineering. Achieving this will require decisive action across the board: from our schools and colleges, to our research labs and science parks.

8. Government Innovation Initiatives So, David what shall we do about this innovation stuff? Do you think Gordon ever did a review?

9. Government Innovation Initiatives _____________________________________________ 1993 Realising our Potential: A Strategy for Science and Technology 1998 Our Competitive Future: Building the Knowledge Economy 1999 Creating Knowledge Creating Wealth: Realising The Economic Potential Of Public Sector Research Establishments 2000 Enterprise, Skills and Innovation: Opportunity for all in a world of change 2000 Excellence and Opportunity: A Science and Innovation Policy for the 21st Century 2002 Delivering the Commercialisation of Public Sector Science 2003 Higher Education Innovation Fund Consultation 2003 BIGTBioscience Innovation and Growth Team 2003 DTI Innovation Review 2003 Lambert Review 2005 RCUK External Challenge for Knowledge Transfer 2005/06 Review of RC Support for Knowledge Transfer 2006 Gowers Review of Intellectual Property 2006 Sainsbury Review of Science and Technology 2006 Increasing the Economic Impact of the Research Councils 2006 Increasing the Economic Impact of the Research Councils

10. The New Mantra EXCELLENCE WITH IMPACT: Warry Report on Economic Impact of Research Councils Recommendation 1: Research Councils should ensure that economic impact is given a high profile in Council strategy Recommendation 2: The Research Councils should influence the behaviour of universities, research institutes and Funding Councils in ways that will increase the economic impact of Research Council funding.

11. Range of Impacts International Development Scientific Advancement Public Health Knowledge Equipment Policy Societal Issues Excellent People Excellent Science Skills Public Engagement Training Communication Schools Wealth Creation New Companies Inward Investment Knowledge Economy Products Jobs Processes

12. Biotechnology and Biological Sciences Research Council Our Mission (Royal Charter) is: - to support high-class science and research training, and to promote knowledge transfer - in support of bio-based industries and public engagement in bioscience. BBSRC funding totals around £450M p.a. STAKEHOLDERS • ACADEMIA • INDUSTRY • PUBLIC • GOVERNMENT

13. Business and Innovation Unit Schemes _____________________________________________ • Funding: • LINK • Industrial Partnerships • Research and Technology Clubs • CASE/Industrial CASE • Industry fellowships • Industry Interchange • KTP • Follow on Fund • Excellence with Impact • Enterprise Fellowships Commercial Awareness Training: • Workshops • Bioscience Exploitation Guide • Young Entrepreneurs Scheme • RC Business Plan Competition • Parliamentary Fellowships

14. BBSRC Innovation Pipeline _____________________________________________

15. Business and Innovation Unit Schemes _____________________________________________ • Funding: • LINK • Industrial Partnerships • Research and Technology Clubs • CASE/Industrial CASE • Industry fellowships • Industry Interchange • KTP • Follow on Fund • Excellence with Impact • Enterprise Fellowships Commercial Awareness Training: • Workshops • Bioscience Exploitation Guide • Young Entrepreneurs Scheme • Bioscience Business Plan Competition • Parliamentary Fellowships

16. BBSRC Bioscience Exploitation Guide Bioscience exploitation guide _____________________________________________

17. Bioscience Exploitation Guide _____________________________________________ • Web-based with accompanying booklet • Signpost bioscientists thinking of commercialising their research to appropriate information sources and expert contacts • cover main areas of commercialisation: - intellectual property - evaluation of market potential - exploitation strategies - funding and investment - help and support networks • use case studies to illustrate key issues

18. Training and Networking Exercise • Regional workshops for teams of upto 5 post docs • Training from experts in the field of biotechnology commercialisation • Prepare a presentation business plan based on imaginary idea • The competition final (for £1000) occurs in December to find a national winner www.biotechnologyyes.co.uk

19. Research Councils Business Plan _____________________________________________ Aims: • to increase awareness of the issues involved in developing a bioscience business, • help the formation of new bioscience business ventures • two stage format - Training - Mentoring • call closed

20. BPC Bioscience Prize Winner 2003-04: Monica Healthcare _____________________________________________ Foetal Health Monitoring Company University of Nottingham

21. BPC Bioscience Prize Winner 2003-04: Monica Healthcare _____________________________________________ 2005 Secured £450k seed investment 2007 Raised further £1m on CE marking 2009 Further £1m for expansion

22. Business and Innovation Unit Schemes _____________________________________________ • Funding: • LINK • Industrial Partnerships • Research and Technology Clubs • CASE/Industrial CASE • Industry fellowships • Industry Interchange • KTP • Follow on Fund • Excellence with Impact • Enterprise Fellowships Commercial Awareness Training: • Workshops • Bioscience Exploitation Guide • Young Entrepreneurs Scheme • RC Business Plan Competition • Parliamentary Fellowships

23. LINK - Collaborative Research _____________________________________________ Nature of Scheme • LINK resources are mainly concentrated in programmes, each addressing a particular area of science and technology & comprising a portfolio of collaborative projects • LINK Franchise: BBSRC also supports ‘stand-alone’ projects which do not fit into an existing programme but which otherwise meet LINK criteria

24. LINK - Collaborative Research _____________________________________________ Criteria • The project must involve collaborative research with at least one company and one research base partner • Maximum funding available to any LINK project from Government/Research Council is 50% of eligible costs • Companies from all areas of UK can participate, SMEs particularly encouraged • Research projects must be pre-competitive in nature and would not be undertaken in absence of LINK support • Research projects must have an appropriate management framework and both scientific and commercial deliverables should be clearly defined • Agreements for ownership & exploitation of IP arising from the project must be agreed by partners

25. Industrial Partnership Awards (IPA) _____________________________________________ • academic/company research project • address any area within BBSRC's remit • industrial contributions must be cash • collaborations with a minimum cash contribution of 10% have a preference for funding

26. Research and Technology Clubs BRIC – Bioprocessing Research Industry Club How to manufacture biotherapeutics more efficiently DRINC – Diet and Health Research Industry Club Bioactives in Food that Benefit Health and Improved Understanding of Healthier Diets IBTI Club – Integrated Biorefining Research and Technology Club

27. Club mechanism: key features • Agreement on generic research areas of industrial relevance • ‘common pot’ funding (RCs/industry) funds 3 calls for applications – 2 stages outline and full application • Industry members subscriptions on sliding scale (company size) • Steering Group with industry and academic representatives • Managed research programme (external coordinator) • Development of a community promoting industry-academic links • Dissemination of results to Industry Members

28. RC Follow-on Fund

29. RC Follow-on Fund • Recognised gap in current support for funds to demonstrate the commercial feasibility of ideas (RCUK Survey) • End of a research grant before market able to pick up with route to commercialisation unclear • The proof-of-concept model where further work on an idea will take it to the point at which the market opportunity can be secured e.g. through licensing, spin – out company (seed or venture finance)

30. RC Follow on Fund _____________________________________________ • What will it fund? • Pathfinder Grants • Small grants up to £10k • Achieve commercial rather than science goals • Market study, external expertise • First Milestone Funding up to £20k Aim is to help write the commercial development plan part of a full Follow on Fund application.

31. RC Follow on Fund _____________________________________________ • How are Pathfinders funded? • Small grants £10k - ish • Maximum duration 6 months - ish • Open Call • Guaranteed 15 working day turn around

32. RC Follow on Fund _____________________________________________ • Follow on Fund : What will it fund? • Undertaking further scientific and technical development • of an idea • Improving an IP position by supporting further • work to broaden patent claims • Gain information about the market for a new products or • process • Identifying potential licensees or opportunities for joint ventures

33. RC Follow on Fund _____________________________________________ • How will it fund? • Small grants £120k - ish • Maximum duration 12 months - ish • BBSRC has funded 80 projects worth £9m (success rate 28%)

34. RC Follow on Fund _____________________________________________ • How will it fund - 2? • BBSRC Panel • Panel drawn from research/industry/TT offices • Each RC has ring fenced funding

35. RC Follow on Fund _____________________________________________ • Call Timetable • No peer review therefore quick • (12 week process from call to award) • Three calls per year for proposals (BBSRC) • 2010 Closing date 20 January Panel 25 February • Closing date 24 June Panel 29 July • Closing date 30 October Panel 2 December

36. RC Follow on Fund _____________________________________________ • What will it not fund? • PhD student or squeezed three year post doc • Basic research • Applied research for companies • Equipment • IP costs eg patents

37. RC Follow on Fund _____________________________________________ • And finally: • BBSRC standard grant conditions apply

38. RC Follow-on Fund • Further details: www.bbsrc.ac.uk/business/followon/welcome.html • Contacts: BBSRC Mary MacDonagh: e-mail:mary.mcdonagh@bbsrc.ac.uk; Tel: 01793 413275 EPSRC David Mahoney: e-mail: david.mahoney@epsrc.ac.uk Tel: 01793 444395 NERC Andrew Richardson: e-mail ajri@nerc.ac.uk, Tel: 01793 411526

39. post proof of concept fellowship • a year's salary to develop a potential spin out company • business training to help prepare a business plan and take idea forward • access to mentors and industrial supervisor • piggy backed to Royal Society of Edinburgh scheme • Calls twice a year for April and October start

40. And finally Thank you donald.mair@bbsrc.ac.uk www.bbsrc.ac.uk Tel: 01793 413293