the biology of atherosclerosis heart attacks and strokes
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The Biology of Atherosclerosis, Heart Attacks and Strokes

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The Biology of Atherosclerosis, Heart Attacks and Strokes. Bryan Holden. First Things First…. What is Atherosclerosis? - It is the progressive depositing of lipids and cells in the inner layer of an artery -It is the most common cause of heart attacks and strokes

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Presentation Transcript
first things first
First Things First…

What is Atherosclerosis?

-It is the progressive depositing of lipids and cells in the inner layer of an artery

-It is the most common cause of heart attacks and strokes

-Accounts for 75% of all cardiovascular disease deaths

the mechanism of a heart attack
The Mechanism of a Heart Attack
  • WBC’s adhere to luminal surface of the artery wall.
  • WBC’s differentiate into macrophages to fight an infection
  • Macrophages can readily endocytose LDL cholesterol into artery
  • Cholesterol is converted to an ester and is passed into the macrophage forming a foam cell
blood clot results in
Blood clot results in…

Heart attack

Stroke

Death

treatments
Treatments

Balloon stretching

Removal of plaques

Stents

Bypass surgery

prevention of atherosclerosis
Prevention of Atherosclerosis
  • Exercise: 30 minutes most of the days of the week
  • Eat a diet low in saturated fats
  • Don’t smoke
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