Membranes. Membrane Functions. A Bit of History. Charles Overton—1890’s Lipid nature of membranes Lipids readily crossed the membrane Polar/charged molecules did not Irving Langmuir—1900’s Phospholipid monolayer. E. Gorter and F. Grendel—1925 RBCs Lipid bilayer
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Lipid bilayer was not enough to describe differential permeability
Differ between layers of the bilayer--assymetric
Evidence for fluidity