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Hershey's work on T2 phage. DNA, not protein is hereditary substance. CONTENT. 1.Hershey History. 2. What is T2??. 3. Infective Cycle. 4. Hershey Chase Experiment. 5. Conclusion. Alfred Day Hershey. His best known experiment is Hershey Chase experiment

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Hershey's work on T2 phage

DNA, not protein is hereditary substance


CONTENT

1.Hershey History

2. What is T2??

3. Infective Cycle

4. Hershey Chase Experiment

5. Conclusion


Alfred day hershey
Alfred Day Hershey

  • His best known experiment is Hershey Chase experiment

  • Concerned the replication of genetic structure of viruses

4 Dec. 1908--- 22 May 1997


1934 -1950Teaching and research at the Department of Bacteriology1936Held an instructorship in bacteriology and immunology 1936 -1939Work together with Professor J. J. Bronfenbrenner. 1938Became assistant professor 1942Became associate professor


What is t2
What is T2 ?

  • The T2 phage is a strongly toxic bacteriophage and tadpole-shaped virus

  • small virus that infect only bacteria

  • Contain 50% DNA and 50% protein


Infect E-coli

  • Contains linear double-stranded DNA



Protein coat of the T2 carries the organ of initiate infection

attachment to bacteria.


The infective cycle of T2 in E.coil initiate infection

  • Virus attach to the surface of their host cell(a)






Hershey chase experiment
Hershey Chase initiate infection Experiment

  • Radioactive Sulphur (35S)

    non-radioative DNA?

  • Radioactive Phosphorous(35P)

    radioactive DNA?


Conclusion initiate infection

DNA is the

GENTIC MARTERIAL!!!


~THE END~ initiate infection


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