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Antihistamines

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Antihistamines

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    1. ?16? ?????? Antihistamines

    2. Histamine? ???? ???, ??, ??? ?? ??? ?? ?????? ?? ???? ???, ?? ???? ??, ????

    3. Antihistamine Antagonists H1 antagonist : ???? ??? ??, ?,?,?? ???? ? allergy ??? ??. ???? ????, ???, ??? ? H2 antagonist : ????? ????? ??? ?? ? ???? ??. ???? ??, ???, ???, ???? ?

    4. ??????? ?? ??

    6. ??-????(H1 antagonist) Aminoalkyl ether(X:O) Ethylenediamine(X:N) Alkylamine(X:CH) Piperazine Phenothiazine ?? ??? ????? ??? ?????? ??????? ??? ?? ??? ?? ???? ??.? potentiates the depressant activity of barbiturate, alcohol, narcotic analgesics and other depressants 1. R,R’? methyl?? ?? ??? ??. 2. ??? 3? ???? ??, ??? pH?? protonation 3.??? ?? imidazole? ??? ?? 4. X? N??? ??? ??? 2 ?? 3?? ????? 5??6 angstrom??? ??? ??

    8. Ethanolamine? ??? ??????

    9. Ethylenediamine? ??????? ???? ? ????

    10. Piperazine? ?????? ???? ? ????

    23. H2 antagonist

    25. Cimetidine? ??

    27. H2 antagonist

    32. ??? ?? ??? (proton pump inhibitor)

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