Rabies in south asia epidemiological investigations
Download
1 / 40

RABIES IN SOUTH ASIA - EPIDEMIOLOGICAL INVESTIGATIONS - PowerPoint PPT Presentation


  • 97 Views
  • Uploaded on

RABIES IN SOUTH ASIA - EPIDEMIOLOGICAL INVESTIGATIONS. C.K.Singh and B.S. Sandhu Rabies Research-cum-Diagnostic Laboratory, Guru Angad Dev Veterinary and Animal Sciences University , Ludhiana , Punjab, INDIA [email protected] Talking from highest prevalence of rabies in Eurasia.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'RABIES IN SOUTH ASIA - EPIDEMIOLOGICAL INVESTIGATIONS' - rich


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
Rabies in south asia epidemiological investigations

RABIES IN SOUTH ASIA- EPIDEMIOLOGICAL INVESTIGATIONS

C.K.Singh and B.S. Sandhu

Rabies Research-cum-Diagnostic Laboratory,

Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana , Punjab, INDIA

[email protected]


Talking from highest prevalence of rabies in eurasia
Talking from highest prevalence of rabies in Eurasia

  • More than 20,000 human deaths occur every year

  • 17.4 million humans are bitten by dogs in India every year

  • Over Rs. 1200 crores are spent annually on post bite vaccination assuming about half of the exposed do not get PET

  • Over 15 Crores is spent on PET in farm animals


The study
The Study

  • The study was conducted on brain tissues collected from a total of 356 animals including 231 dogs, 79 buffaloes and 46 cows.

  • The brain tissues of only those animals that were suspected to be suffering from rabies clinically were included in this study.


Impression smear from hippocampus of a rabid dog showing magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875


Section of Hippocampus of a rabid dog magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875showingintra-cytoplasmic eosinophilic Negri bodies ( arrows )in neurons. H&E x875


Incidence in animals
Incidence in animals magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875

  • SuspectedConfirmed

  • 356 201

  • 231 dogs 128 dogs

  • 79 buffaloes 44 buffaloes

  • 46 cows 29 cows


Initial signs of rabies
Initial Signs of Rabies magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875

  • Rabid Dogs

  • About half the rabid dogs go off feed & show change in behavior few exhibit fever. Ocular involvement is rare.

  • Rabid Cows

  • Almost every rabid cow goes off feed and about half the rabid cows exhibit fever. Few rabid cows exhibit ocular involvement .

  • Rabid Buffaloes

  • Majority of rabid buffaloes go off feed and more than half exhibit fever. Majority of buffaloes show ocular involvement .


Most susceptible age sex
Most susceptible Age/Sex magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875

  • Incidence in higher in adult dogs (>3 Yrs.) and pups (<6 M). The incidence is minimum in 6 M to 3 Years dogs.

  • The higher incidence of rabies in male dogs is largely due to their gregarious wandering and furious nature especially during breeding season.


Signs symptoms dogs v s bovines
Signs & Symptoms - magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875Dogs v/s Bovines

  • Only 24 percent rabid dogs show hyper salivation that is characteristic for bovines. So, Veterinarian need not look for clinical hypersalivation while suspecting dog rabies.

  • Only 30 % rabid dogs show paralysis . Paralysis is not necessarily the end sign in dogs.


Signs symptoms dogs v s bovines1
Signs & Symptoms - magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875Dogs v/s Bovines

  • About half of the rabid dogs continue to recognize their owner

  • Most rabid cows and buffaloes fail to recognize their owners


Signs symptoms dogs v s bovines2
Signs & Symptoms - magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875Dogs v/s Bovines

  • More than half (61%) of all rabid animals show aggressive behavior. Majority of aggressive rabid dogs inflict bite wounds to humans and/or other animals.

  • Aggression of bovines is limited to inflicting trauma to themselves. No rabid bovine ever bites other animals and/or humans.


Bovines similarity bellowing in bovines
Bovines - Similarity magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875Bellowing in Bovines

  • Majority of both cows and buffaloes (66%) reveal prolonged and prominent fits of loud bellowing


Bovines differences drooling saliva 32 v s 86
Bovines - Differences magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875Drooling Saliva -32% v/s 86%

  • Drooling saliva is often reported as the characteristic feature in rabies in bovines

  • It was found that hyper salivation was exhibited by less than half (32%) of rabid buffaloes

  • However, hyper salivation was more commonly exhibited (86%) by rabid cows.


Bovines differences micturition in bovines
Bovines - Differences magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875Micturition in Bovines

  • Rabid Cows

  • Reveal frequent micturition

  • Rabid Buffaloes

  • Frequent micturition is not common in buffaloes


Month wise incidence
Month-wise Incidence magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875

  • Increased incidence in dogs was reported during January, February, July and November.

  • Increased incidence in buffaloes was observed during January to March

  • Increased incidence in cattle was observed during March, April, June, August, October and November


Major area of concern
Major Area of Concern magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875

  • 78% of owned rabid dogs were not vaccinated prophylactically.

  • There is high incidence of rabies in owned/community dogs.


Merci magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875


Characteristics of rabid dogs magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875


Characteristics of rabid cows magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875


Characteristics of rabid buffaloes magenta colored intracellular Negri body (arrow) in a neuron. Seller’s stain x875


ad