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Applying for a Grant at the NIH. Helen Quill, Ph.D. Chief, Basic Immunology Branch Division of Allergy, Immunology & Transplantation NIAID, NIH. The Application Process. 2 Independent Assignments for Your Grant Application upon Receipt at NIH. Peer Review

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slide1

Applying for a Grant at the NIH

Helen Quill, Ph.D.

Chief, Basic Immunology Branch

Division of Allergy, Immunology & Transplantation

NIAID, NIH

slide6

Peer Review

“Before you criticize someone, you should walk a mile in their shoes. That way when you criticize them, you’re a mile away and you have their shoes.”

-Steven Wright

csr center for scientific review
CSR (Center for Scientific Review)

Study Section

peer review panel

15-25 reviewers, mostly from academia

IRG (integrated review group)

group of study sections

new immunology irg
New Immunology IRG

New Study Sections: est. June 2004

Innate Immunity & Inflammation (III)

Immunity & Host Defense (IHD)

Cellular & Molecular Immunology (CMI)-A

Cellular & Molecular Immunology (CMI)-B

Hypersensitivity, Autoimmune & Immune-Med. Dis. (HAI)

Transplantation, Tolerance & Tumor Immunology (TTT)

Vaccines Against Microbial Diseases (VMD)

F32 Postdoctoral Grants

institute program officer
Institute Program Officer

Designated Federal official with overall

responsibility for the funding process

  • Scientist trained in area of coverage
  • Develops targeted research programs
  • Approves funding and oversees funded grants
  • Approves yearly progress reports
  • Assists PI with both administrative & scientific questions
  • Attends study section as observer
review process
Review Process

6-8 wks before study section meeting

SRA assigns and sends applications to primary, secondary, tertiary reviewers (mostly academics) for evaluation

At study section meeting

- These 3 reviewers give initial scores

- Primary presents research plan, discusses PI, etc.

- Secondary emphasizes points of agreement/disagreement

- Tertiary adds his/her 2 cents worth

- General discussion/questions among panel members

- All panel members vote a priority score

Less expected from new PI

review process1
Review Process

1-2 months after review

- SRA prepares summary statement (written critique document) and calculates percentiles (R01s)

- CSR or Institute mails summary statement to PI

~5 months after review

Institute sends Notice-of-Grant Award by e-mail to PI’s business office

paylines
Paylines
  • Payline is based on percentile (rank)
  • Percentile: your score percentiled against current scores in that study section plus the previous 2 rounds of review in that study section
  • Each Institute determines its own payline (e.g. in 2003, NIAID 22.0%; NCI 20.0%)
  • Payline may be different from prior fiscal year
  • For most Institutes, percentiles within the payline get funded automatically
  • Study sections may recommend budget/time cuts; Institutes usually follow these recommendations
slide18

K08Mentored Clinical Scientist Development Award

  • Clinical doctoral degree only
  • US citizenship or green card
  • 3-5 yrs of support
  • Salary: up to $75K + FB/yr
  • Supplies: up to $20K/yr
  • 75% effort required
k23 mentored patient oriented research career development award
K23Mentored Patient-Oriented Research Career Development Award
  • M.D. or Ph.D. working with patients
  • US citizen or green card
  • Candidates just out of specialty or sub-specialty training
  • Project must be patient-oriented research
  • 3-5 yrs of support
  • Salary: up to $75K + FB/yr
  • Supplies: $25K/yr
  • 75% effort required
k22 research scholar development award
K22Research Scholar Development Award
  • Postdoc moving to assistant professor
  • Eligibility
    • Current NIAID intramural postdoc
    • Current postdoc on NIAID training grant/fellowship
    • US citizen or green card
  • 2 yrs non-renewable
  • Yr 1: $150K; yr 2: $100K
  • Can apply without a sponsoring institution
success rates for niaid training and career development grants
Grant Type

F32

K02

K08

K22

K23

K24

T32

OVERALL

2002 Success Rate (%)

25

63

66

59

39

27

60

43

SUCCESS RATES FOR NIAID TRAINING AND CAREER DEVELOPMENT GRANTS
how nih staff can help you
How NIH Staff Can Help You

CSR Scientific Review Administrator (SRA)

Before review

Advice on study section, amount of preliminary data, supplementary data, etc.

how nih staff can help you1
How NIH Staff Can Help You

Institute Program Officer

Before review

Scientific advice on proposed Aims; on revised Aims; on study section, etc.

After review

  • Discuss review, summary statement, revision
  • Provide information on payline, funding status
  • Rarely – help with funding outside the payline
how nih staff can help you2
How NIH Staff Can Help You

Use the Institute Program Officer

as your point person at NIH

websites
Websites
  • NIH Home Page: www.nih.gov
  • Training/Career Development: www.training.nih.gov
  • Grant Guidelines/Forms:
  • www.nih.gov/grants/documentindex.htm
  • How to Write a Grant:

www.niaid.nih.gov/ncn/grants/write/index.htm

  • NIH Guide:
  • http://grants.nih.gov/grants/guide/index.html
  • NIAID Solicited Biodefense Research Programs:
  • www.niaid.nih.gov/biodefense
new immunology irg1
New Immunology IRG

New Study Sections: est. June 2004

Innate Immunity & Inflammation (III)

Immunity & Host Defense (IHD)

Cellular & Molecular Immunology (CMI)-A

Cellular & Molecular Immunology (CMI)-B

Hypersensitivity, Autoimmune & Immune-Mediated Diseases (HAI)

Transplantation, Tolerance & Tumor Immunology (TTT)

Vaccines Against Microbial Diseases (VMD)

F32 Postdoctoral Grants

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