Applying for a Grant at the NIH
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Applying for a Grant at the NIH. Helen Quill, Ph.D. Chief, Basic Immunology Branch Division of Allergy, Immunology & Transplantation NIAID, NIH. The Application Process. 2 Independent Assignments for Your Grant Application upon Receipt at NIH. Peer Review

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Applying for a grant at the nih

Applying for a Grant at the NIH

Helen Quill, Ph.D.

Chief, Basic Immunology Branch

Division of Allergy, Immunology & Transplantation

NIAID, NIH


Applying for a grant at the nih

The Application Process


2 independent assignments for your grant application upon receipt at nih

2 Independent Assignments for Your Grant Application upon Receipt at NIH


Applying for a grant at the nih

Peer Review

“Before you criticize someone, you should walk a mile in their shoes. That way when you criticize them, you’re a mile away and you have their shoes.”

-Steven Wright


Csr center for scientific review

CSR (Center for Scientific Review)

Study Section

peer review panel

15-25 reviewers, mostly from academia

IRG (integrated review group)

group of study sections


New immunology irg

New Immunology IRG

New Study Sections: est. June 2004

Innate Immunity & Inflammation (III)

Immunity & Host Defense (IHD)

Cellular & Molecular Immunology (CMI)-A

Cellular & Molecular Immunology (CMI)-B

Hypersensitivity, Autoimmune & Immune-Med. Dis. (HAI)

Transplantation, Tolerance & Tumor Immunology (TTT)

Vaccines Against Microbial Diseases (VMD)

F32 Postdoctoral Grants


Institute program officer

Institute Program Officer

Designated Federal official with overall

responsibility for the funding process

  • Scientist trained in area of coverage

  • Develops targeted research programs

  • Approves funding and oversees funded grants

  • Approves yearly progress reports

  • Assists PI with both administrative & scientific questions

  • Attends study section as observer


Review process

Review Process

6-8 wks before study section meeting

SRA assigns and sends applications to primary, secondary, tertiary reviewers (mostly academics) for evaluation

At study section meeting

- These 3 reviewers give initial scores

- Primary presents research plan, discusses PI, etc.

- Secondary emphasizes points of agreement/disagreement

- Tertiary adds his/her 2 cents worth

- General discussion/questions among panel members

- All panel members vote a priority score

Less expected from new PI


Review process1

Review Process

1-2 months after review

- SRA prepares summary statement (written critique document) and calculates percentiles (R01s)

- CSR or Institute mails summary statement to PI

~5 months after review

Institute sends Notice-of-Grant Award by e-mail to PI’s business office


Paylines

Paylines

  • Payline is based on percentile (rank)

  • Percentile: your score percentiled against current scores in that study section plus the previous 2 rounds of review in that study section

  • Each Institute determines its own payline (e.g. in 2003, NIAID 22.0%; NCI 20.0%)

  • Payline may be different from prior fiscal year

  • For most Institutes, percentiles within the payline get funded automatically

  • Study sections may recommend budget/time cuts; Institutes usually follow these recommendations


Applying for a grant at the nih

Funding Mechanisms


Applying for a grant at the nih

K08Mentored Clinical Scientist Development Award

  • Clinical doctoral degree only

  • US citizenship or green card

  • 3-5 yrs of support

  • Salary: up to $75K + FB/yr

  • Supplies: up to $20K/yr

  • 75% effort required


K23 mentored patient oriented research career development award

K23Mentored Patient-Oriented Research Career Development Award

  • M.D. or Ph.D. working with patients

  • US citizen or green card

  • Candidates just out of specialty or sub-specialty training

  • Project must be patient-oriented research

  • 3-5 yrs of support

  • Salary: up to $75K + FB/yr

  • Supplies: $25K/yr

  • 75% effort required


K22 research scholar development award

K22Research Scholar Development Award

  • Postdoc moving to assistant professor

  • Eligibility

    • Current NIAID intramural postdoc

    • Current postdoc on NIAID training grant/fellowship

    • US citizen or green card

  • 2 yrs non-renewable

  • Yr 1: $150K; yr 2: $100K

  • Can apply without a sponsoring institution


Success rates for niaid training and career development grants

Grant Type

F32

K02

K08

K22

K23

K24

T32

OVERALL

2002 Success Rate (%)

25

63

66

59

39

27

60

43

SUCCESS RATES FOR NIAID TRAINING AND CAREER DEVELOPMENT GRANTS


R01 success rates all pis

R01 Success Rates (%)All PIs


R01 success rates new pis nih wide

R01 Success Rates (%)New PIs NIH-wide


Solicited research programs nih institutes

Solicited Research ProgramsNIH Institutes


Applying for a grant at the nih

Help


How nih staff can help you

How NIH Staff Can Help You

CSR Scientific Review Administrator (SRA)

Before review

Advice on study section, amount of preliminary data, supplementary data, etc.


How nih staff can help you1

How NIH Staff Can Help You

Institute Program Officer

Before review

Scientific advice on proposed Aims; on revised Aims; on study section, etc.

After review

  • Discuss review, summary statement, revision

  • Provide information on payline, funding status

  • Rarely – help with funding outside the payline


How nih staff can help you2

How NIH Staff Can Help You

Use the Institute Program Officer

as your point person at NIH


Spend some time at the nih and niaid websites

Spend some time at the NIH and NIAID websites!


Websites

Websites

  • NIH Home Page: www.nih.gov

  • Training/Career Development: www.training.nih.gov

  • Grant Guidelines/Forms:

  • www.nih.gov/grants/documentindex.htm

  • How to Write a Grant:

    www.niaid.nih.gov/ncn/grants/write/index.htm

  • NIH Guide:

  • http://grants.nih.gov/grants/guide/index.html

  • NIAID Solicited Biodefense Research Programs:

  • www.niaid.nih.gov/biodefense


New immunology irg1

New Immunology IRG

New Study Sections: est. June 2004

Innate Immunity & Inflammation (III)

Immunity & Host Defense (IHD)

Cellular & Molecular Immunology (CMI)-A

Cellular & Molecular Immunology (CMI)-B

Hypersensitivity, Autoimmune & Immune-Mediated Diseases (HAI)

Transplantation, Tolerance & Tumor Immunology (TTT)

Vaccines Against Microbial Diseases (VMD)

F32 Postdoctoral Grants


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