Allergy in a ‘nutshell’ GP guide to survival. Dr Gillian Vance. Allergy care. Starts with early diagnosis. Session. Better understanding of the basic immunological mechanisms underlying food allergic disease Apply mechanisms to clinical evaluation & appropriate therapy . Objectives.
Dr Gillian Vance
Starts with early diagnosis
Anaphylaxis risen 7-fold; 5/million 1990/1- 36 2003/4
Food allergy risen 7-fold; 16 - 107/million
Urticaria doubled; 20 – 44/million – especially children
BSACI, London, commissioned study, 2002
Th2-biased cytokine production
Smooth muscle contraction
Cow’s milk, Egg white, Soybean, Wheat, Peanut, Tree nuts, Fish & Shellfish account for >90% reactions
‘KISS OF DEATH FOR NUT ALLERGY GIRL’
A teenage girl with an extreme allergy has died after kissing her boyfriend who had eaten a peanut-butter sandwich hours earlier.
Christina Desforges, 15, from Saguenay, Canada, went into anaphylactic shock. She was given an adrenalin shot and taken to hospital but died four days later from acute respiratory failure.
Doctors said that a nut allergy brought on by the kiss was the cause of death. The boy, who has not been named, had minute traces of peanut on his lips.
Macdougall et al, 2002, Arch Dis Child