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SLEEPING SICKNESS

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SLEEPING SICKNESS - PowerPoint PPT Presentation


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SLEEPING SICKNESS. WHAT IS?. SLEEPING SICKNESS IS A PARASITIC DISEASE OF PEOPLE AND ANIMALS, CAUSED BY PROTOZOA OF THE SPECIES TRYPANOSOMA BRUCEI  AND TRANSMITTED BU THE TSETSE FLY. THE DISEASE IS ENDEMIC IN SOME REGIONS OF SUB-SAHARAN AFRICA.

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what is
WHAT IS?
  • SLEEPING SICKNESS IS A PARASITIC DISEASE OF PEOPLE AND ANIMALS, CAUSED BY PROTOZOA OF THE SPECIES TRYPANOSOMA BRUCEI AND TRANSMITTED BU THE TSETSE FLY.
  • THE DISEASE IS ENDEMIC IN SOME REGIONS OF SUB-SAHARAN AFRICA.
  • THE PARASITE IS UNABLE TO SURVIVE IN THE BLOODSTREAM WITHOUT ITS FLAGELLUM.
signs and symptoms
SIGNS AND SYMPTOMS:
  • AFRICAN TRYPANOSOMIASIS SYMPTOMS OCCURS IN TWO STAGES:
  • THE HAEMOLYMPHATIC PHASE: (FEVER-HEADACHES-JOINT PAINS-ITCHING)
  • THE NEUROLOGICAL PHASE: (CONFUSION-REDUCED COORDINATION-DISRUPTION OF THE SLEEP CYCLE- FATIGE, SLUMBER [DAY-TIME]-INSOMNIA [NIGHT-TIME]
  • TRYPTOPHOL: CHEMICAL COMPOUND THAT INDUCES SLEEP IN HUMANS PRODUCED BY THE TRYPANOSOMAL PARASITE.
tsetse fly
TSETSE FLY:
  • LARGE, BROWN BITING FLY.
  • HOST AND VECTOR (TRYPANOSOME PARASITES).
  • FIRST, PARASITES ENTER THE LYMPAHATIC SYSTEM, THEM PASS INTO THE BLOODSTREAM AND REPLICATE BY BINARY FISSION.
  • OTHER WAYS TO TAKE THE DISEASE:
  • MOTHER TO CHILD INFECTION
  • LABORATORIES
  • BLOOD TRANSFUSION
  • SEXUAL CONTACT
prevention
PREVENTION:

THE STRATEGY USED TO CONTROL SLEEPING SICKNES IS DETECTION AND TREATMENT OF NEW INFECTIONS, TSETSE FKY CONTROL.

  • ERADICATION OF THE TSETSE FLY.
  • REDUCE SPREAD OF THE PARASITE.

SYSTEMATIC SCREENING IS THE BEST OPTION(ENDEMNIC REGIONS). ALLOWS EARLY-STAGE DISEASE TO BE DETECTED AND TREATED BEFORE THE DISEASE PROGRESSES.

treatment
TREATMENT:
  • IN THE HAEMOLYMPHATIC PHASE:
  • INTRAVENOUS OR INTRAMUSCULAR PENTAMIDINE.
  • INTRAVENOUS SURAMIN.
  • IN THE NEUROLOGICAL PHASE:
  • INTRAVENUS MELARSOPROL 2.2 MG/KG DAILY FOR 12 HOURS.
  • INTRAVENOUS EFLORNITHINE 50 MG/KG EVERY SIX HOURS FOR 14 DAYS.
spreading
SPREADING:
  • TRYPANOSOMA BRUCEI GAMBIENSE. HUMANS, ALSO IN PIGS AND OTHER ANIMALS. LOCATED IN CENTRAL AND WESTERN AFRICA.
  • TRYPANOSOMA BRUCEI RHODESIENSE. WILD GAME ANIMALS AND CATTLE. LOCATED IN SOUTHERN AND EASTERN AFRICA.
  • OVER 60 MILLION PEOPLE ARE AT RISK OF CONTRACTING THE DISEASE.
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RESOURCES:
  • http://en.wikipedia.org/wiki/African_trypanosomiasis
  • http://www.google.es/search?tbm=isch&hl=es&source=hp&biw=1280&bih=675&q=sleeping+sickness&gbv=2&oq=sleeping+sic&aq=0&aqi=g1g-S9&aql=&gs_sm=e&gs_upl=2231l11331l0l13554l14l14l1l1l1l0l287l2484l0.6.6l12l0

BY:JACQUELINE VALLEJO FERNÁNDEZ

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