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Part 2. Transcription 1. Transcription 2. Translation 1. Translation 2. Mutations. 100. 100. 100. 100. 100. 200. 200. 200. 200. 200. 300. 300. 300. 300. 300. 400. 400. 400. 400. 400. 500. 500. 500. 500. 500.

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Presentation Transcript
slide2

Transcription

1

Transcription

2

Translation

1

Translation

2

Mutations

100

100

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100

200

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slide3

Where does transcription take place? (name part of eukaryotic cell)What are copied from DNA during transcription?

slide5

What are the sites on Prokaryotes called that regulate gene expression during transcription?

Why is gene regulation important in Eukaryotes?

slide6

Regulatory

Sites

Regulatory Sites Without these gene expression could not be controlled (turn on or off) in Prokaryotes

Gene regulation in Eukaryotes allows for cell specialization

Transcription #1 200

slide14

T A C A C G C A G A T T (DNA)A U G U G C G U C U A A(mRNA)Each codon has 3 nucleotides eachTranscription #2 100

transcription 2 300

Introns

Out!

“junk”

Transcription #2 300

Exons In!

slide21

What is the part of a Eukaryote’s DNA that signals where the RNA polymerase is to begin transcribing?

Hint:

transcription 2 500

The TATA Box is the promoter

region in eukaryotes

for transcription.

Transcription #2 500

out of the nucleus and into the cytoplasm to the ribosome translation 1 100

Out of the nucleus and into the cytoplasm to the ribosomeTranslation #1 100

Cytoplasm

translation 1 300

Begins at the “Start” codon AUG

(Remember: It’s the month we start school)

AUG codes for Methionine (Met)

Translation #1 300

what happens to the amino acids that are brought to the ribosome by the trna s during translation

What happens to the amino acids that are brought to the ribosome by the tRNA’s during translation?

Amino

Acid

slide30

Amino

Acid

The amino acid joins the growing polypeptide chain (protein). The tRNA then leaves to find another amino acid.

Translation #1 400

when a stop codon is reached on the mrna strand translation 1 500

When a STOP codon is reached on the mRNA strand.Translation #1 500

Stop

codon

Polypeptide chain released into cytoplasm

and the ribosome falls off of the mRNA which

is disposed of by the cell.

Translation #1 500

slide33

Translate this mRNA

A U G U G C G U C U A A

mrna a u g u g c g u c u a a amino acids

mRNA A U G U G C G U C U A AAmino Acids

Met

Cys

Val

Stop

This is TRANSLATION!!!

Translation #2 100

what does this wheel show

What does this wheel show?

What process is taking place when you use this wheel?

translation 2 200

Translation #2 200

Shows the GENETIC CODEThe process is TRANSLATION

translation 2 300

Threonine

ACG

ACA

ACCACU

6 is the maximum number or codons possible for an amino acid!

Translation #2 300

slide40

tRNA

brings

1

Amino

Acid

Translation #2 400

slide42

Different codons

Different amino acids

Translation #2 500

slide45

Of the following mutations, which one of these is not a gene mutation?SubstitutionDeletion InsertionInversion

Gene mutation in mice.

slide46

Substitution = Point Mutation (gene)Deletion = Frame Shift Mutation (gene)Insertion = Frame Shift Mutation (gene)

Inversion = Chromosomal Mutation

I bet he can catch 3x more flies!

Mutations for 200

name all types of chromosomal mutations

Name all types of chromosomal mutations

slide52

Hox Genes

NOT a real picture!!!

Mutations for 500

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