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GFR = K f · {(P C - P BS ) - ( p C - p BS )}

GFR = K f · {(P C - P BS ) - ( p C - p BS )}. Efferent Arteriole. Afferent arteriole. P C. - Constriction of afferent arteriole. P C ¯. GFR ¯. - Constriction of efferent arteriole. P C. GFR. (but RBF falls in both cases). K f. (e.g.; Glomerulonephritis ). P BS. GFR.

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GFR = K f · {(P C - P BS ) - ( p C - p BS )}

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  1. GFR = Kf · {(PC - PBS) - (pC - pBS )} Efferent Arteriole Afferent arteriole PC - Constriction of afferent arteriole PC¯ GFR ¯ - Constriction of efferent arteriole PC GFR (but RBF falls in both cases) Kf (e.g.; Glomerulonephritis) PBS GFR (congestion of urine in urinary syst.) pC - Increases by dehydration GFR - decreases by hunger GFR pBS (normal » 0) - increases by deseases of glomerula RPF GFR Factors affecting GFR Peff = (PC- PBS) - (pC-pBS) ≈ 0 RPF (600 ml·min-1) RPF-GFR (480 ml·min-1) pC PC GFR (120 ml·min-1) PBS 50 40 Pressure (mmHg) 30 PC 20 pC 10 PBS 0

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