Healthgrid Systems Experiences from International Projects

1. Healthgrid Systems Experiencesfrom International Projects • David MANSET • Director of BiomedicalApplications • CEO MAAT France • www.maat-g.com

2. maat – Stages of Growth 2004- Stage 3 1998- Stage 1 2000- Stage 2 2007- Stage 4 Growth Idea Start-Up Development Foundation Process Virtual Knowledge & Maat Gknowledge Incubation, I+D+i, Raising Public Awareness Partners Network Maat Gknowledge Internationalization

3. maat Portfolio (1) Horizontal Solutions Data Warehouse Grid Integration SaaS

4. maat Portfolio (2) Vertical Solutions • Is about Core Banking • Integrated transactional banking system • CRM, • Wealth management, • Corporate banking, • Trade Finance, • Functional services • Is about e-Administration • Faciliate access to information, • Electronic access points, • Security and privacy on citizens data, • System interoperability, • eServices to citizens such as electronic transactions, • - Compliant with LAECAP law • Is about Healthcare ICT • Research infrastructure, • Multi-level data integration, • Multi-centre network, • Security and privacy conformance, • Multi-backends abstraction, • DICOM compliant Public Administration Healthcare SMEs - ERP Education RAD Web Banking

5. maat Portfolio (3) Grid

6. maat Portfolio (3) An Inter-Disciplinary Middleware-Agnostic Web Operating System *Courtesy of SIEMENS

7. Awards in 1 Year Time.. HeC/maatranked 1st Best Live Demo at the 2008 HealthGrid Conference, June in Chicago, US maat received a “Gold Medal” Award at the 2007 “Salon International des Inventions de Genève” for its prototype Healthgrid Platform HeC/maatwon Grand Prize - Best Exhibit 1st Prize at the 2008 ICT Conference, November in Lyon, France  10’000€ Maat quoted as “Cool Vendor” by GARTNER in Platform and Integration Middleware HeC/maat ranked in Top 5 Best Live Demos, qualified as “Runners Up” at the 2007 EGEE Conference last October in Budapest , Hungary for its Healthgrid Platform HeC/maat ranked 1st Best Live Demo at the 2008 EGEE User Forum, February in Clermont-Ferrand, France for its Healthgrid Platform and Innovative Applications

8. Internet Grid The worldwide network of networks... Web The environment for sharing computing resources over the Web... The protocol for sharing Information over the Internet... *Courtesy of EGEE Project Healthgrid (1) The Internet, the Web and the GRID

9. System Architecture (1/2) Layered View & Concepts Portal (A series of *web* interfaces exposing the functionality to end-users from login, to data acquisition, quality control, Workflow authoring ... and much more! The Portal approach beyond accessibility advantages, allows harmonizing the software offer) Business Logic (NeuroSciences Specific Services) Privacy (All services necessary to guaranty privacy Over medical data storage, access and Sharing. Privacy related services must conform with ethical EU/National regulations) Workflow Management (SOA Governance is in charge of defining, accessing, executing, operating and maintaining reusable services with appropriate quality of services and conforming with all other requirements, e.g. Security, privacy...) Security (All services concerned with authentication, authorization within the neuGRID platform) Domain Logic (Medical Generic Services)‏ Monitoring, Logging and Accounting (Provides the mechanisms to store, archive and sort all log information. The layer is concerned with services which allow efficient monitoring of all infrastructure resources , and from which higher level logic such as Provenance can extract useful historical data) Backends Abstraction (Software abstraction from databases, grid, enactment environments...) Backends Middleware (Underlying IT legacy assets, e.g. EGEE gLite, mySQL, LONI, Oracle 11g...)

10. System Architecture (2/2) Layered View & Concepts Portal (A series of *web* interfaces exposing the functionality to end-users from login, to data acquisition, quality control, Workflow authoring ... and much more! The Portal approach beyond accessibility advantages, allows harmonizing the software offer) HighlySpecialized Interfaces Common Purpose Interfaces Business Logic (NeuroSciences Specific Services) Specific to Project (cantheoreticallybepartlyreusedsince abstractedfromunderlying IT) Privacy (All services necessary to guaranty privacy Over medical data storage, access and Sharing. Privacy related services must conform with ethical EU/National regulations) Workflow Management (SOA Governance is in charge of defining, accessing, executing, operating and maintaining reusable services with appropriate quality of services and conforming with all other requirements, e.g. Security, privacy...) Security (All services concerned with authentication, authorization within the neuGRID platform) Domain Logic (Medical Generic Services)‏ Monitoring, Logging and Accounting (Provides the mechanisms to store, archive and sort all log information. The layer is concerned with services which allow efficient monitoring of all infrastructure resources , and from which higher level logic such as Provenance can extract useful historical data) Generic to Medicaldomain (cantheoreticallybereused in othermedical applications) Backends Abstraction (Software abstraction from databases, grid, enactment environments...) Generic to ALL domains (cantheoreticallybefullyreused) Backends Middleware (Underlying IT legacy assets, e.g. EGEE gLite, mySQL, LONI, Oracle 11g...)

11. Mammogrid+A Grid-powered Mammography Database Healthgrid Healthgrid(1) • Second Opinion • Cancer Screening • Education and Training • ReferenceDatabase / Repository

12. neuGRIDA Grid-based e-Infrastructure for Data Archiving and Computing Intensive Applications in neurosciences Healthgrid Healthgrid(2) • BiomarkersAssessment • BiomarkersAuthoring • Extension to OtherMedical Areas • ReferenceDatabase & Infrastructure QuestionA Marker of Alzheimer’s progression?

13. Pharmaco-EpidemiologyMulti-centre Pharma Grid-basedData Warehouse for Epidemiological Studies Healthgrid Healthgrid(3) • EpidemiologicalStudies • ScalableDataware House • ScalableStatisticalAnalysis • TranslationalResearch • ReferenceDatabase

14. Health-e-Child, An Healthgrid for Paediatrics Healthgrid Healthgrid(4) • Decision Support • Vertical Data Integration • KnowledgeDiscovery • ReferenceDatabase of Rare Conditions

15. SENTINELLE NetworkBreast and Colon Cancer Screening,Surveillance Network Healthgrid Healthgrid(5) • Breast Cancer Screening • Colon Cancer Screening • Surveillance, Alert and Monitoring Network

16. SPIDeRSuper Peta-scale Infrastructure for Distributed e-health and biomedical Research Healthgrid Healthgrid (6) • SPIDeR Web • A Super Infrastructure of about • 6000 CPUs, • 100TB, • 15 new dedicated sites Neurology SilkenBags Epidemiology Silk Collaborations Drug Development http://spider.healthgrid.org

17. + + + + + + + + + + + Infrastructure ASPER KI MAAT COL VUmc UCL GOSH UWE SIEMENS Clinical Site PRODEMA MAAT CERN NECKER R&D Site IGG FBF FGG CETA EGF HG CIEMAT CFC INDRA DISI UOA OPBG INRIA SIEMENS MAAT LYNKEUS JHU

18. CADe Breast Cancer DSS Paediat. Cancer Alzheimer Biomarker UWE Healthgrid + + + + + Marketing Plan (1) Healthgrid 2005 2006 2008 Mammogrid+ Health-e-Child neuGRID

19. CADe Breast Cancer DSS Paediat. Cancer Alzheimer Biomarker • Infrastructure • - Teaming-up with Telco Operators (i.e. Telefonica) • - Sustainable platform and infrastructure • - Strong position in the market and its big sales network (not only in Spain but worldwide) • - Opened infrastructure to Consultancy and Systems Integrator firms (i.e. Indra, Entel) + + + + + + Marketing Plan (2) A Network of Certified Partners - Support in porting new applications to HGSP - Online & Offline education services - OnDemand infrastructure and data for application training - Access to infrastructure facilities for promoting new products - Direct access to market (i.e. Network of Clinical Institutions) - Certification process and official label for software - Possibility to sell online consultancy - Education careers: technicial (presales, maintenance and support, and operation) and sales/marketing Healthgrid A Network of Clinical Institutions - User Support - Online & Offline Education Services (from HGSP and from Certified Partners) - Access to a large network of excellence at minimal cost - Access to state-of-the-art software from Certified Partners - Provide data for enriching the infrastructure THANK YOU FOR YOUR ATTENTION!