NITROGEN METABOLISM
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NITROGEN METABOLISM. Nitrogen is essential for all organisms (in amino acids and nucleic acids). Most of the conversions between organic and inorganic nitrogen are catalyzed by bacterial and archaeal enzymes. oxidative. reductive. fungi. plants. animals. Urea cycle:

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NITROGEN METABOLISM

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Nitrogen metabolism

NITROGEN METABOLISM


Nitrogen metabolism

Nitrogen is essential

for all organisms

(in amino acids and

nucleic acids).

Most of the conversions

between organic

and inorganic

nitrogen are catalyzed

by bacterial and

archaeal enzymes.

oxidative

reductive

fungi

plants

animals


Nitrogen metabolism

Urea cycle:

Lose two amino-N

and a CO2

Follow the N from

carbamoyl-P

(green arrow) and

the N from aspartate

(red arrow).

How much energy

does it take to

remove two

amino-nitrogens?


Nitrogen metabolism

How many of the reactions that we have studied are represented in excretion

of excess nitrogen?


Nitrogen metabolism

  • Summary

  • Nitrogen enters the biosphere through plants, fungi, but mainly

  • bacteria and archaea

  • Plants, fungi, and bacteria reduce nitrate nitrogen to ammonium

  • Ammonium is incorporated into organic molecules by glutamate

  • dehydrogenase and glutamine synthase/GOGAT

  • Other amino acids are formed by transamination

  • The urea cycle removes nitrogen from ammonia and alanine

  • as urea


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