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INTAS’ funding instruments for integration of NIS Food Science/ Biotechnology into the European Research Area EU-Russia Symposium & Brokerage on Biotechnology 14-16 March 2005 Moscow, Russia Paul Beckers, Scientific Officer for Life Sciences. The essence of INTAS Evolving context

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  1. INTAS’ funding instruments for integration of NIS Food Science/ Biotechnology into the European Research Area EU-Russia Symposium & Brokerage on Biotechnology14-16 March 2005Moscow, RussiaPaul Beckers, Scientific Officer for Life Sciences

  2. The essence of INTAS Evolving context Pre-view of INTAS activities 2005-2006 FP6 Information transfer activities Conclusions Outline

  3. The essence of INTAS Evolving context Pre-view of INTAS activities 2005-2006 FP6 Information transfer activities Conclusions Outline

  4. INTAS • INTAS – International Association for the promotion of co-operation with scientists from the New Independent States of the former Soviet Union (NIS) Established in 1993 to: • preserve the best NIS scientific capabilities • foster social & economic progress • support international scientific collaboration for mutual benefit

  5. Members & Partners 25 European Union member states + European Community Bulgaria Iceland Israel Norway Romania Switzerland Turkey 12 Partner Countries Armenia Azerbaijan Belarus Georgia Kazakhstan Kyrgyzstan Moldova Russia Tajikistan Turkmenistan Ukraine Uzbekistan 33 Members

  6. INTAS Structure Council of Scientists Scientific advisory body NIS & MS Proposes list of projects to fund General Assembly Decision making body MS Approves list of projects to fund Approves budget 3 2 INTAS Secretariat Executive body Calls/projects management 1-4 Scientific communities of NIS and INTAS members

  7. INTAS budget Major part comes from the European Community (International Cooperation) 2002 - 2006 ~70 M Euro In kind contributions from members + financial participation from members & NIS in jointly funded projects 2002 – 2006 ~10 M Euro

  8. INTAS Priorities • Search for scientific excellence • Cover allscientific areas • Include fundamental andapplied research • Support internationalscientific collaboration • Select proposals on the basis of independent evaluations • Allocate min. 75% of the funds to NIS teams • Focus on young scientist initiatives • Opening the European Research Area to NIS countries ao by increasing participation in FP6 and next FP´s

  9. ”Cooperation activities with Russia and other NIS countries will be carried out in particular through the INTAS structure set up jointly by the Community and the Member States.” (Council Decision adopting the specific FP6 programme “Integrating and strengthening the European Research Area”) INTAS and FP62002-2006

  10. Agreements INTAS Agreements on Scientific Cooperation with: Armenia Belarus Georgia Kazakhstan Kyrgyzstan Moldova Russian Federation: Russian Foundation for Basic Research, Russian Foundation for the Humanities Tajikistan Ukraine Uzbekistan

  11. Agreements INTAS Agreements on Scientific Cooperation for: • "framework" agreements • tax exemptions of INTAS grants • duty-free import of INTAS-funded scientific equipment • official contact person in ministry / state committee

  12. The essence of INTAS Evolving context Pre-view of INTAS activities 2005-2006 FP6 Information transfer activities Conclusions Outline

  13. Evolving context INTAS defines its new position in a more complex reality: • Uneven development in different NIS countries • ERA as a key element in European Union • Agreements on Co-operation in S&T • EU-Russia development of Common Spaces • EU Neighbourhood policy

  14. New tools to develop/ implement the scientific policy New balance between open and thematic calls Maintain focus on young scientists More focus on innovation and technology transfer Co-funding and co-operation partnerships Industry INTAS new focus

  15. Planned activities • Development of INTAS scientific policy tools: scientific policy workshops, kick-off meetings • Calls for proposalsfor research projects and networks: open calls, thematic & jointly funded calls • Pre-/Post PhD Fellowshipsfor young NIS scientists • Accompanying Measures : Summer Schools, Infrastructure Actions, Conference grants • Innovation Grants : dissemination and exploitation of research results • ININ(INTAS FP6 NIS Information Network): Promotion of NIS participation in FP6 & ERA All presented activities are subject to approval by the INTAS General Assembly

  16. The essence of INTAS Evolving context Pre-view of INTAS activities 2005-2006 FP6 Information transfer activities Conclusions Outline

  17. 1.Development of INTAS scientific policy tools: Scientific policy workshops to - Identify priorities, trends and needs Refine scope of calls for proposals Kick-off meetings after launching a call Organised by INTAS steering committees based on an annual list approved by the Council of Scientists Envisaged calls

  18. 2. Calls for proposalsfor research projects and networks: Open call 2005 for scientific excellence Two stage procedure;1. Pre-proposal containing consortium, summary of objectives and research programmeOpen April <->Close Mid June (to be confirmed)2. Full proposal containing detailed tasks, cost tableOpen September <-> Close January (to be confirmed) Maximum 150,000 € per project Envisaged calls

  19. 2. Calls for proposalsfor research projects and networks: Thematic callGenomics and proteomics research for health (including food and environmental impact) Two stage procedure;1. Pre-proposal containing consortium, summary of objectives and research programmeOpen April <->Close Mid June (to be confirmed)2. Full proposal containing detailed background, tasks, cost tableOpen September <-> Close January (to be confirmed) Maximum 150,000 € per project Envisaged calls

  20. Thematic callGenomics and proteomics research for health (including impact of food and environment) Focus on - molecular mechanisms of infectious diseases (Tuberculosis, AIDS) and cancer - genetic background of an individuals` immunological response to them - integration and updating annotation of genomics/ proteomics data Envisaged calls

  21. 3. Pre-/Post PhD Fellowshipsfor young NIS scientists PhD fellowships Postdoc fellowships 2 years 2 years, 2 visits (4-8 months) Duration 2 years, 2 visits (6-12 months) Funding Funding Monthly allowances according to local standards plus travel Working towards PhD & Continue for 2 years from Beginning of fellowship Be in full time research position at NIS organisation during the fellowship Eligibility Envisaged calls Objective:incentives for young NIS scientists to pursue a career in NIS science,networking with European institutes, complementarity with FP mobility programme.

  22. 3. Collaborative YSF calls Envisaged calls Objective: establishing a reliable and flexible framework for co-funding with European national and international entities and collaboration with national governmental structures from the NIS. Open or Thematic focus: to be determined with co-funding partner

  23. 4. Accompanying measures- Summer school support; core-list & case by case- Conference grants for: individual NIS scientists support for organisation- Infrastructure support on a case by case basis (initiatives like E-library) Envisaged calls

  24. 5. Innovation grants Objective Promote further development, utilisation and marketing of INTAS research results (significant economic &/or social value) Envisaged calls Minimum partnership 2 contractors  1 from the NIS (individual or private/public organisation) 1 from INTAS members (private or public organisation) Involve at least 1 participant of original project Funding 25 000 € per innovation grant not more than 25% of total to all contractors of INTAS members

  25. INTAS Calls 2005 in short Subject to the availability of funds • Thematic Call on Genomics and Proteomics for health 1,5 M € • Thematic Call on Sustainable Energy Systems 1,5 M € • Open Call 12 M € • Collaborative Call with CERN To be confirmed • Collaborative Call with Moldova To be confirmed • Collaborative Call with Georgia To be confirmed Launching April/May 05 Deadline September 2005 Expected results December 05 Expected earliest start March 06

  26. INTAS Calls 2005 INTAS Young Scientist Fellowships 2,5 M € INTAS Innovation Grants 500,000 € Expected launching May 05 Expected Deadline September 05 Expected results December 05 Expected earliest start March 06 INTAS Accompanying Measures Summer schools 300,000 € Conference grants to be determined Infrastructure Actions to be determined

  27. The essence of INTAS Evolving context Pre-view of INTAS activities 2005-2006 FP6 Information transfer activities (ININ) Conclusions Outline

  28.  INTAS FP6 NIS Information Network ININ Established to promote the involvement of NIS scientific communities in European Research Area (ERA), and their participation in Sixth Framework Programme for Research & Technology(FP6)

  29. INTAS Contacts in NIS • Help provided to scientific communities in the NIS • About INTAS through the INTAS Information Desks (Armenia, Belarus, Georgia, Russia) • complete list and contact details on www.intas.be in “Links” • About FP6 and European Programmes through the INTAS National Information Points / National Contact Points • (Armenia, Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Ukraine, Uzbekistan) • complete list and contact details on www.intas.be in “ININ”

  30.  ININ Concept ININ Activities • Information dissemination & networking • Scientific community-targeted activities / events • Support to NIS FP6 NIS National Information Points (NIP)/ National Contact Points (NCP)

  31.  ININ Information dissemination ININ • POISK FP6 series (11 articles ’03, 12 articles ’04) • Regular mailings • INTAS Website

  32.  National Information Points (NIPs) ININ Typical tasks: modelled on the NCPs • Information & awareness raising about ERA, FP6 & international S&T co-operation • Advice, assistance & training • “Signposting” (feed-back & reporting) • Monitoring of domestic research communities

  33.  National Information Points (NIP/ NCP) ININ Status • NIP structures appointed in 10 NIS • NIP coordinators information & training workshops (meetings with FP6 officials & NCPs, spring ‘03) • NIP concept papers (long term objectives & strategy) • Agreements for ININ support to NIPs (Sept. 2003 – Feb. 2005) • NIP capacity-building training courses (March-April ’04)

  34.  ININ next steps ININ • More scientific community-targeted activities: • Brokerage events scheme • Reflection on other partner search support activities • Increased cooperation with INTAS members & international organisations

  35.  Brokerage event on S&T collaboration in Food/Biotech, March 2005, Moscow ININ • More scientific community-targeted activities: • Matching EU and NIS scientists with common interests • Providing tailor made information about funding schemes • Establish and maintain partnering catalog for follow up

  36. The essence of INTAS Review of INTAS 1992-2003 Pre-view of INTAS activities 2005-2006 FP6 Information transfer activities Conclusions Outline

  37. INTAS can offer more than 10 years of experience in funding EU-NIS collaborative science INTAS defines new funding instruments/ structures for integrating NIS scientists into FP/ERA Established structure of NIP/ NCPs facilitates EU-NIS partnering INTAS is looking for partnerships in collaborative and co-funded actions Conclusions

  38. For Life Sciences: Paul.Beckers@intas.be In general: INTAS@intas.be INTAS Contact

  39.  Scope Food Call 2000 • Production, processing and distribution of food. • Environmental impact of food production, processing and distribution. • Improvements in human and animal health as a result of plant and animal breeding, dietary changes, reduced toxicity, quality control, food safety, etc. • Social and economic consequences of changes in food production, processing and distribution.

  40.  Facts and Figures Food Call 2000 • Budget 1.2 M€ • 16 Projects • 80 Teams • 22 Countries (3UZ; 6UK; 11UA; 2SE; 25RU; 2NL; 2MD; 3KZ; 4IT; 1IL; 1IE; 2GR; 3GE; 1FR; 1FI; 2ES; 1DK; 4DE; 1CH; 1BY; 3AT; 2AM)

  41. Food Call 2000

  42. Highlights Food Call 2000 003-0471 Bases for a rational control of foodborne listeriosis: a paneuropean initiative Teams: University of Leon, Spain Veterinary School, University of Bristol, UK All Russia Meat Institute, Moscow, Russia Gamalleya Research Institute of Epidemiology and Microbiology, Moscow, Russia Research Institute of Veterinary Virology and Microbiology, Pokrov, Russia Institute for Milk Hygiene, Milk Technology and Food Science, Vienna, Austria Duration: 01-10-2001 till 30-09-2005

  43. Highlights Food Call 2000 • Bases for a rational control of foodborne listeriosis: a paneuropean initiative • Objectives: • Elaboration of rapid methods for the detection and typing of Listeria monocytogenes strains present in the food chain, from the farm to the ready-to-eat food. • Investigation of Listeria monocytogenessurvival, growth and virulence in environmental models, simulating natural habitants like soil, food and animal tissues; • Comparative epidemiological analysis of clinical and food-borne isolates of L. monocytogenes from all around Europe to get insight into the relationships between epidemiological, physiological and virulent characteristics of the strains; • Study of the genetic and physiological bases of listerial survival, growth and virulence expression under specific stress conditions observed in food models.

  44. Highlights Food Call 2000 • Bases for a rational control of foodborne listeriosis: a paneuropean initiative • Outcome (so far): • RFLP analysis supports hypothesis of three phylogenetic lineages of L. monocytogenes • New method to differentiateL. monocytogenes from non-pathogenic Listeria spp. based on lecithinase activity on charcoal-supplemented agar media • Establishment of the State Standard of the Russian Federation for methods of detection of Listeria monocytogenes in food products • 1 Patent (Russian Federation N2196827; adopted 20-01-2003) • 3 joint papers in international journals; 5 in national journals; 1 thesis

  45. Highlights Food Call 2000 Bases for a rational control of foodborne listeriosis: a paneuropean initiative Outcome (so far): Figs. Rapid method of identification of L. monocytogenes food isolates based on the induction of lecithinase in charcoal-supplemented egg yolk medium. (From: Ermolaeva et al. 2003, Int. J. Food Microbiol. 82:87-94; Ermolaeva et al. 2004. Mol. Microbiol. 52:601-611.)

  46. Highlights Food Call 2000 003-0727 Prevention of food spoilage by suppression of phenoloxidase, peroxidase and growth of pathogenic microflora by use of natural inhibitors of plant origin Teams: University of Murcia, Spain John Innes Centre, Norwich, UK Kazan Institute of Biochemistry and Biophysics, Kazan, Russia Institute of Bacteriophage, Microbiology and Virology, Tblisi, Georgia Georgian State Subtropical Institute, Kutaisi, Georgia Durmishidze Institute of Biochemistry and Biotechnology, Tblisi, Georgia Duration: 01-07-2001 till 31-05-2004

  47. Highlights Food Call 2000 • Prevention of food spoilage by suppression of phenoloxidase, peroxidase and growth of pathogenic microflora by use of natural inhibitors of plant origin • Objectives: • to obtain and characterize highly active inhibitors of phenoloxidases and peroxidases isolated from different plants • to determine the mechanism of inhibition of plant phenoloxidases and peroxidases by natural inhibitors of plant origin • to determine the antibacterial activity of isolated biologically active substances towards different groups of food spoilage microorganisms and pathogenic bacteria • to determine the effect of compounds of plant origin on the energy exchange of plants • to investigate the effect of plant inhibitory preparations on the generation of superoxide radicals and the activity of ascorbate oxidase in model plant cells • to prevent spoilage, extend shelf life and preserve the nutritional value of food products using natural inhibitors of plant origin.

  48. Highlights Food Call 2000 • Outcome (so far): • Several phenoloxidases and peroxidases from different plant sources have been isolated and characterized. • Purification protocols for natural inhibitors from tea (Cameliia sinenisis L) leaves and pomegranate (Punica granatum) peel have been developed. • New, improved types of the beer and butter with longer shelf lives and increased nutritional value have been produced by adding these natural inhibitors and green / black tea extracts to the currently marketed products. • The data demonstrated that natural plant inhibitors can be used for the prevention of bacterial spoilage and contamination of food products while maintaining a viable, high level of beneficial microflora. • First evidence that the prophylactic effect of green tea drinking on certain forms of cancer, suggested by epidemiological studies, is due to the inhibition of dihydrofolate reductase (DHFR) by (-)-epigallocatechin gallate EGCG. • 11 papers in international journals (5 jointly; 2 in press; 4 submitted); 3 in national journals; 1 publication in a book; 4 abstracts in proceedings; 1 patent

  49. Highlights Food Call 2000 003-0876 New biotechnologies for production of food grade lactic acid from raw starchy material Teams: Technical University of Hamburg- Harburg, Germany Wageningen Agricultural University, The Netherlands Republican Centre for Deposition of Microorganisms, National Academy of Science, Armenia St. Petersburg State Technological Institute (technical University), Russia Institute of Microbiology, National Academy of Science, Minsk, Belarus Duration: 01-08-2001 till 31-07-2003

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