Slacker s guide to neurotransmitters
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Slacker’s Guide to Neurotransmitters. Prepared by Mike Ori. Disclaimer. Slackers please continue but note… The summary was taken from our class notes and PowerPoint slides. They reflect my understanding and could be wrong. The faculty has in no way vetted this document.

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Slacker’s Guide to Neurotransmitters

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Slacker s guide to neurotransmitters

Slacker’s Guide to Neurotransmitters

Prepared by Mike Ori


Disclaimer

Disclaimer

  • Slackers please continue but note…

    • The summary was taken from our class notes and PowerPoint slides. They reflect my understanding and could be wrong.

    • The faculty has in no way vetted this document.

    • I’m really uncertain of anything with (?) or in red.

    • If you see something wrong, let me know.

If you’re a gunner, shame on you for looking at this. Do your own work.


Slacker s guide to neurotransmitters

Key

Increase

A lot

A lot

Decrease

A lot is relative. I used it when there were (++) indicators in the text.


Slacker s guide to neurotransmitters

CNS

Memory

Sleep

Dementia

Delirium

Alzheimer

Awake

PTSD

Autism

Slow Wave Sleep

Basal N.

ARAS

REM Sleep

Cholinergic

Basal Nucleus

ARAS

Choline

Acetate

ACh

Choline Acetyltransferase

Cord/interneurons

PNS

Parasympathetic

Sympathetic

Skeletal

Ganglion

Ganglion

NMJ

Myasthenia Gravis*

Muscarinic

Effector

*Net effect is as if there is a decrease in Ach


Slacker s guide to neurotransmitters

CNS

Well Being

Movement

ADHD?

Schizophrenia

Huntington

Addiction

Parkinson

VTA

SNC

Dopaminergic

Ventral tegmental Area

SubstantiaNigra

Catecholamine

Tyrosine

L-DOPA

Dopamine

Tyrosine

Hydroxylase

(Limiting)

DOPA

Decarboxylase

(Carbidopa inhibits)

Parasympathetic

PNS

Sympathetic

Skeletal

None detailed in class but peripheral effects of PD treatment cause GI upset.


Slacker s guide to neurotransmitters

CNS

Well Being

OCD

Eating Disorders

Depression

Anxiety

Tourette

Raphe

Serotonergic

AKA: 5-HT

Raphe nuclei

Tryptophan

Serotonin

Tryptophan

Hydroxylase

(Limiting)

Parasympathetic

PNS

Sympathetic

Skeletal

Descending pain modulation by GABA disinhibition of PAG


Slacker s guide to neurotransmitters

CNS

Well Being

Memory

Sleep

ADHD

Depression

PTSD

Awake

Slow wave sleep

Anxiety

LC

Adrenergic

Locus Ceruleus

Catecholamine

REM Sleep

Tyrosine

Norepinephrine

Tyrosine

Hydroxylase

(Limiting)

PNS

Parasympathetic

Sympathetic

Skeletal

Ganglion

Descending pain modulation by GABA disinhibition of PAG

None described in class

Effector


Slacker s guide to neurotransmitters

CNS

Thalamic Reticular

Cortical Regulation

Well Being

inattentive

Seizure

Anxiety

Gabaergic

Increase GABA to slow brain activity

If its inibited, think GABA

Glutamate

GABA

Glutamic acid decarboxylase

(Limiting)

PNS

Parasympathetic

Sympathetic

Skeletal

Descending pain modulation by GABA disinhibition of PAG. Most likely neurotransmitter in any inhibitory synapse


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