Dengue fever a worldwide crisis
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Used with permission from Microsoft. Dengue fever: a worldwide crisis. Abigail Jeffers MPH Student Walden University PUBH 6165-4 Environmental Health Dr. Robert P. Marino Winter Quarter 2010. agenda. Expected learning outcome Understand cost to society Recognize impact on health

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Dengue fever: a worldwide crisis

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Dengue fever a worldwide crisis

Used with permission from Microsoft

Dengue fever: a worldwide crisis

Abigail Jeffers

MPH Student

Walden University

PUBH 6165-4 Environmental Health

Dr. Robert P. Marino

Winter Quarter 2010


Agenda

agenda

  • Expected learning outcome

  • Understand cost to society

  • Recognize impact on health

  • Develop effective control

  • Describe infection routes

  • Audience

  • WHO

  • CDC

  • Government

  • General population

  • Purpose of presentation

Used with permission from Microsoft


What is it

What is it?

  • Mosquito-borne viral disease

  • DENV-1

  • DENV-2

  • DENV-3

  • DENV-4

  • Endemic to Tropical regions

  • No cure

  • DHF

Used with permission from Microsoft

Center for Disease Control and Prevention. (2010). Epidemiology. Retrieved from http://www.cdc.gov/dengue/epidemiology/index.html


Cause of dengue fever

Cause of dengue fever

  • Bite from infected Aedes aegypti mosquito

  • Stagnant water

  • Poor surveillance

  • Poor Control

  • Poorly constructed homes

  • Solid waste disposal

Used with permission from CDC

World Health Organization. (2009). Dengue and dengue hemorrhagic fever. Retrieved from http://www.who.int/mediacentre/factsheets/fs117/en/


Lifecycle of aedes aegypti

Lifecycle of aedes aegypti

Used with permission from Hopp & Foley, 2001


Endemic regions

Endemic regions

Used with permission from World Health Organization. (2009). Dengue and dengue hemorrhagic fever. Retrieved from http://www.who.int/mediacentre/factsheets/fs117/en/


Symptoms treatment

Symptomstreatment

  • Fever 105ºF

  • Rash

  • Headache

  • Backache

  • Petechiae

  • Ecchymoses

  • Supported care

  • Acetaminophen

  • Rehydration

  • Blood pressure control

  • Transfusions

Used with permission from Microsoft

Used with permission from Microsoft

Gurugama, P., Garg, P., Perera, J., Wijewickrama, A. & Seneviratne, S.L. (2010). Dengue Viral Infections. Indian J Dermatol, 55(1):68-78. DOI: 10.4103/0019-5154.60357


Prevalence

prevalence

  • 100 million cases per year

Used with permission from Microsoft

Center for Disease Control and Prevention. (2009). Dengue Fact Sheet. Retrieved from http://www.cdc.gov/dengue/faqFacts/fact.html


Incidence

incidence

  • 2.5 billion people

  • 2/5 of the world's population

  • 500,000 DHF cases

  • 120 million travellers

Used with permission from Microsoft

World Health Organization. (2011). Dengue/dengue hemorrhagic fever. Retrieved from http://www.who.int/csr/disease/dengue/en/


Morbidity

morbidity

  • Children

  • Elderly

Used with permission from Microsoft

Schwartz, E., Weld, L.H., Wilder-Smith, A., von Sonnenburg, F., Keystone, J.S., Kain, K.C., Torresi, J. & Freedman, D.O. (2008). Seasonality, annual trends, and characteristics of dengue in ill returned travelers, 1997–2006. Emerging Infectious Diseases, 14(7):1081-1088. DOI: 10.3201/eid1407.071412


Mortality

mortality

  • 2.5% of children

  • >20% w/o proper treatment

  • 22,000 deaths per year

Image shows the gut of a mosquito filled with blood during feeding.

Used with permission from CDC

Center for Disease Control and Prevention. (2010). Epidemiology. Retrieved from http://www.cdc.gov/dengue/epidemiology/index.html


Outbreaks

outbreaks

  • 2007 Venezuela

  • 2007 Puerto Rico

  • 2008 Brazil

  • 2009 Cape Verde

  • 2010 The Americas

Used with permission from Google images

Ribeiro, P. (2009). 2008 Dengue fever outbreak in Rio de Janeiro . Retrieved from http://gobrazil.about.com/od/denguefeverinbrazil/a/denguerio.htm


Cost to society

Cost to society

  • Funds availability

  • Decreases GDP

  • Economic strain

  • $1.8 billion annually

  • Loss of income

Used with permission from Microsoft

Center for Disease Control and Prevention. (2009). Dengue Fact Sheet. Retrieved from http://www.cdc.gov/dengue/faqFacts/fact.html

Gubler, D.J. (2006). Dengue/dengue hemorrhagic fever: history and current status. U.S. National Library of Medicine, 277:3-16. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17319151

Suaya, J.A., Shepard, D.S., Siqueira, J.B., Martelli, C.T., Lum, L.C., Tan, L.H., Kongsin ,S., Jiamton, S,. Garrido, F., Montoya ,R., Armien, B., Huy, R., Castillo, L., Caram, M., Sah, B.K., Sughayyar ,R., Tyo, KR. & Halstead, S.B. (2009). Cost of dengue cases in eight countries in the Americas and Asia: a prospective study. American Journal of Tropical Medicine Hygiene, 80(5):846-855. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/19407136


Prevention and control

Prevention and control

  • Eradicating the mosquitoes

  • Eliminating stagnant water

  • Use of mosquito pesticide

  • Testing of blood products

Used with permission from Microsoft

Gurugama, P., Garg, P., Perera, J., Wijewickrama, A. & Seneviratne, S.L. (2010). Dengue Viral Infections. Indian J Dermatol, 55(1):68-78. DOI: 10.4103/0019-5154.60357


Challenges

challenges

  • Community involvement

  • Physicians knowledge

  • Increased air travel

  • Urbanization

Used with permission from Microsoft

Center for Disease Control and Prevention. (2009). Dengue Fact Sheet. Retrieved from http://www.cdc.gov/dengue/faqFacts/fact.html


References

references

  • Center for Disease Control and Prevention. (2009). Dengue Fact Sheet. Retrieved from http://www.cdc.gov/dengue/faqFacts/fact.html

  • Center for Disease Control and Prevention. (2010). Epidemiology. Retrieved from http://www.cdc.gov/dengue/epidemiology/index.html

  • Gubler, D.J. (2006). Dengue/dengue hemorrhagic fever: history and current status. U.S. National Library of Medicine, 277:3-16. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17319151

  • Gurugama, P., Garg, P., Perera, J., Wijewickrama, A. & Seneviratne, S.L. (2010). Dengue Viral Infections. Indian J Dermatol, 55(1):68-78. DOI: 10.4103/0019-5154.60357

  • Ribeiro, P. (2009). 2008 Dengue fever outbreak in Rio de Janeiro . Retrieved from http://gobrazil.about.com/od/denguefeverinbrazil/a/denguerio.htm

  • Suaya, J.A., Shepard, D.S., Siqueira, J.B., Martelli, C.T., Lum, L.C., Tan, L.H., Kongsin ,S., Jiamton, S,. Garrido, F., Montoya ,R., Armien, B., Huy, R., Castillo, L., Caram, M., Sah, B.K., Sughayyar ,R., Tyo, KR. & Halstead, S.B. (2009). Cost of dengue cases in eight countries in the Americas and Asia: a prospective study. American Journal of Tropical Medicine Hygiene, 80(5):846-855. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/19407136


References1

References

  • Schwartz, E., Weld, L.H., Wilder-Smith, A., von Sonnenburg, F., Keystone, J.S., Kain, K.C., Torresi, J. & Freedman, D.O.(2008). Seasonality, annual trends, and characteristics of dengue in ill returned travelers, 1997–2006. Emerging Infectious Diseases, 14(7):1081-1088. DOI: 10.3201/eid1407.071412

  • Ugonabo, N., & Valdovinos, C. (2008). Assessing the impact of treatment of septic tanks with expanded polystyrene beads on Aedes aegypti larval and adult mosquito emergence. Retrieved from http://www.stanford.edu/group/parasites/ParaSites2008/Nkem_Cristina%20Valdoinos/ugonabon_valdovinosc_dengueproposal.htm

  • World Health Organization. (2009). Dengue and dengue hemorrhagic fever. Retrieved from http://www.who.int/mediacentre/factsheets/fs117/en/

  • World Health Organization. (2011). Dengue/dengue hemorrhagic fever. Retrieved from http://www.who.int/csr/disease/dengue/en/


Supplemental reading

supplemental reading

  • Ballenger-Browning, K.K. & Elder, J.P. (2009). Multi-modal Aedes aegypti mosquito reduction interventions and dengue fever prevention. Tropical Medicine and International Health, 14(12):1542-1551. doi:10.1111/j.1365-3156.2009.02396.x. Use the Walden Library Academic Search Premier database, and search using the article’s Accession Number: 2010496140

  • National Institute of Allergy and Infectious Diseases. (2009). Dengue Fever. http://www.niaid.nih.gov/TOPICS/DENGUEFEVER/RESEARCH/Pages/Default.aspx


Thank you

I sincerely appreciate the time that you have devoted to my presentation. If you have any questions, I will be happy to

answer them.

Thank you!!!

Used with permission from Microsoft


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