The architecture of the PTP1B active site
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Phe180 PowerPoint PPT Presentation


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The architecture of the PTP1B active site. Phosphotyrosine (Substrate). Phe180. Gln262. Q-loop. pTyr-loop. Tyr46. Asp181. WPD-loop. PTP-loop. Arg221. Cys215. http://ptp.cshl.edu or http://science.novonordisk.com/ptp. Courtesy of Dr. Robert Del. Vecchio.

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Phe180

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Phe180

The architecture of the PTP1B active site

Phosphotyrosine

(Substrate)

Phe180

Gln262

Q-loop

pTyr-loop

Tyr46

Asp181

WPD-loop

PTP-loop

Arg221

Cys215

http://ptp.cshl.edu or http://science.novonordisk.com/ptp

Courtesy of Dr. Robert Del. Vecchio


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