Cellular Movement and Muscles. Cellular movement. Movement is a property of all cells. Some cells (such as this amoeba) can move through their environment. All cells can move components through the cytoplasm (such as the vesicles in this amoeba). Cytoskeleton and Motor Proteins.
Movement is a property of all cells
Some cells (such as this amoeba) can move through their environment
All cells can move components through the cytoplasm (such as the vesicles in this amoeba)
Composed of actin and microtubules
Fluorescently labeled cell
Actin – red
Microtubules – green
Nuclei - blue
A microtubule can grow or shrink from either end
MAPs: Microtubule associate proteins
Bind to microtubulues and stabilize or destabilize structure
Motor proteins can move along microtubules
Hoenger, A., Thormählen, M., Diaz-Avalos, R., Doerhoefer, M., Goldie, K.N., Müller, J. and Mandelkow, E. (2000) A new look at the microtubule binding patterns of dimeric kinesins. J Mol Biol, 297, 1087-103.
Myosin moves along actin
Figure 18-22, Lodish 4th edition. The sliding-filament assay