Today:. Quiz 7 Hormones and the Endocrine System. How Does an Animal Body Communicate to Coordinate Function?. Two Options The nervous system Signaling Molecules! (the Endocrine System ) Types and Functions??. Types of Signaling Events. Types of Hormones.
Hormones and the Endocrine System
Types and Functions??
Usually categorized by structure and mode of synthesis.
Useful Idea: Where will the targets of each of these molecules have to be???
Can trigger activation of enzymes, uptake or secretion, rearrangement of cytoskeleton, or transcription changes
How should your blood sugar level respond to a surge in epinephrine (adrenaline)?
Vitellogenin Gene Expression in Male Fathead Minnow as an Indicator of Exposure to Endocrine Disrupting Chemicals (EDCs) in an Aquatic Environment
To develop molecular tools for monitoring fish exposures to EDCs implicated in feminization of male fish around the world and in USA, that are present in surface waters, effluents from sewage treatment plants and sediments
In Anaphylaxis, patients experience bronchial constriction and systemic vasodilation...
Can be paracrine (from neighboring cells) or autocrine (same cell)
Examples: cytokines, growth factors, nitric oxide (NO), prostoglandins
Homeostatic challenges in your duodenum??
Ideal Blood Sugar: 90-100mg/100mL
Balanced by two negative feedback loops (antagonists!)
Neurohormones play critical functions in reproduction and metamorphosis in invertebrates
Example: prophoracicotrophic hormone (PTTH) triggers ecdysis and metamorphosis
Hypothalmus: endocrine gland in the brain of vertebrates
Oxytocin: Positive-feedback mechanism involved in release of milk from mammary glands and uterine contraction
What would an Anti-Diuretic Hormone (ADH) do? When would I produce it?
These impacts make GH tempting for adult athletes to abuse!
A few hormones, like Growth Hormone (GH) have both tropic and nontropic effects
LONDON – In a major breakthrough in the fight against doping, a British rugby league player has become the first athlete to be suspended for using human growth hormone.
Terry Newton admitted taking the substance in a statement released by his attorneys on Friday. The United Kingdom Anti-Doping authority announced a two-year ban on Monday after Newton was fired by his club, Wakefield.
"It's the first time and very significant," WADA director general David Howman said. "It shows the people who say that HGH cannot be detected that it can. The sports people who said it can't be detected are fooling themselves."
Rugby player makes history with growth hormone ban
By ROBERT MILLWARD, AP Sports Writer Robert Millward, Ap Sports Writer – Mon Feb 22, 2010 2:48 pm ET
Involved in both homeostasis (blood pressure, heart rate, etc.) and development
Excessive secretion = hyperthyroidism (high temp, high blood pressure, weight loss)
Insufficient production = hypothyroidism (weight gain, lethargy, intolerance to cold)
Iodine was added to salt in 1924 when up to a third of US adults suffered from goiter!