Proteins
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Proteins. Proteins:. Multipurpose molecules. insulin. pepsin. collagen (skin). Proteins . Examples muscle skin, hair, fingernails, claws collagen, keratin pepsin digestive enzyme in stomach insulin hormone that controls blood sugar levels. Proteins. Function:

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Proteins

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Proteins


Proteins:

Multipurpose molecules


insulin

pepsin

collagen (skin)

Proteins

Examples

  • muscle

  • skin, hair, fingernails, claws

    • collagen, keratin

  • pepsin

    • digestive enzyme in stomach

  • insulin

    • hormone that controls blood sugar levels


Proteins

  • Function:

    • many, many functions

      • hormones

        • signals from one body system to another

        • insulin

      • movement

        • muscle

      • immune system

        • protect against germs

      • enzymes

        • help chemical reactions


H

|

—C—

|

H

amino

acid

amino

acid

amino

acid

amino

acid

amino

acid

C—OH

—N—

O

||

H

Proteins

  • Building block =

amino acids

  • 20 different amino acids

There’s20 of us…

like 20 differentletters in analphabet!Can make lots of differentwords

variable group


amino acid

amino acid

amino acid

amino acid

amino acid

Amino acid chains

  • Proteins

    • amino acids chained into a polymer

  • Each amino acid is different

    • some “like” water & dissolve in it

    • some “fear” water & separate from it


Water-fearing amino acids

  • Hydrophobic

    • “water fearing” amino acids

    • try to get away from water in cell

      • the protein folds


Water-loving amino acids

  • Hydrophillic

    • “water loving” amino acids

    • try to stay in water in cell

      • the protein folds


collagen

For proteins: SHAPE matters!

  • Proteins fold & twist into 3-D shape

    • that’s what happens in the cell!

  • Different shapes = different jobs

growthhormone

hemoglobin

pepsin


It’s SHAPE that matters!

  • Proteins do their jobs, because of their shape

  • Unfolding a protein destroys its shape

    • wrong shape = can’t do its job

    • unfolding proteins = “denature”

      • temperature

      • pH (acidity)

unfolded“denatured”

In Biology,

it’s not the size,

it’s the SHAPEthat matters!

folded


Let’s EAT some

Proteins!


Activities

  • demo raw egg vs. cooked egg

    • drop raw egg into boiling water, like egg drop soup

    • compare raw egg to hard-boiled egg

  • demo cheese-making with heated milk & vinegar

  • make yogurt


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