Eu support for health research from fp6 to fp7
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EU support for Health Research: from FP6 to FP7. Beatrice Lucaroni Unit F4 DG Research - European Commission. Ferrara – 25 Ottobre 2006. EU Health Research. Perspectives for the 7 th Framework Programme.

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Eu support for health research from fp6 to fp7

EU support for Health Research:from FP6 to FP7

Beatrice Lucaroni

Unit F4

DG Research - European Commission

Ferrara – 25 Ottobre 2006


Eu health research

EU Health Research

  • Perspectives for the 7th Framework Programme

  • The details of the FP7 priorities and modalities are still in negotiation and subject to change. In particular the EC’s proposal for the Joint Technology Initiative for Innovative Medicines will be subjected to the approval of the European Council.


Role of ec in research

European Commission programmes bring down barriers

betweencountries:

multinational consortia in Europe (EU-25 + associated countries)

researchers from almost any country in the world can participate;

and promotes coordination of national funding programmes (ERA)

between different types oforganizations:universities, research centres, SMEs, large companies, etc.

betweendisciplines: focus on translational research

and encourages mobility: Marie Curie fellowships for researchers and for host institutes, including ingoing & outgoing grants.

Role of EC in research


Ec research framework programme 6 2003 2006

EC Research Framework Programme 6 (2003-2006)

  • €2.4 billion in research grants for 604 projects in 4 years

  • Average success rate for projects: 25.4%

  • Total number of participants: 7,426


Special call for sme projects in health research 2006

355 proposals received: 86 projects funded

€ 200 million granted: 43% going to SMEs

Average budget requested per SME: € 342,000

~270 SMEs involved (41% of participants)

40/86 projects (46%) coordinated by SMEs

Observations:

SMEs taking leading role in projects

projects aligned with SME’s strategy

SME gaining experience in EC funding schemes

Special call for SME projectsin Health research (2006)


Fp7 main elements

Budget to be increased: €50.5 billion over 7 years + 40%

European Research Council ( Ideas )

Collaborative research ( Cooperation )

continuity in themes & instruments.

funding levels to be raised in some cases, eg SMEs: 50%  75%

Joint Technology Initiatives

Infrastructures, SMEs, regions & potential ( Research Capacities )

Human potential and science careers ( People )

Reminder:

The European Commission currently manages about 5% of total public spending in R&D in the European Union.

The EU currently invests about 1.9% of GDP in research

FP7: main elements


Fp7 budget eur billion 2004 constant prices

FP7 budget(EUR billion, 2004 constant prices)


Eu support for health research from fp6 to fp7

Cooperation: Collaborative researchin FP7

Thematic Priorities

  • Health

  • Food, agriculture and biotechnology

  • Information and communication technologies

  • Nanosciences, nanotechnologies, materials and new production technologies

  • Energy

  • Environment (including climate change)

  • Transport (including aeronautics)

  • Socio-economic sciences and the humanities

  • Security and space

    + Euratom: fusion energy research, nuclear fission and radiation protection


Eu support for health research from fp6 to fp7

Collaborative researchfor Health in FP7

Main policy drivers:

Improving health of European citizens

Increasing competitiveness of European health-related industries and businesses

Addressing global health issues, including emerging epidemics


Collaborative research for health in fp7

Collaborative researchfor Health in FP7

  • Budget:

  • €6 billion over 7 years (2007-2013)

Activities in 3 main areas

Biotechnology, generic tools and technologies for human health

Translating research for human health

Optimising the delivery of healthcare


Collaborative research for health in fp71

Collaborative researchfor Health in FP7

1:Biotechnology, generic tools and technologies

High-throughput research enhancing data generation, standardisation, acquisition & analysis

Detection, diagnosis and monitoring with emphasis on non-invasive or minimally invasive approaches

Innovative therapeutic approaches and interventionsgene and cell therapy, regenerative medicine, transplantation, immunotherapy and vaccines, implants & prosthetics

Predicting suitability, safety and efficacy of therapies develop and validate parameters, tools, methods and standards (mainly through IMI) and alternatives to animal testing


Collaborative research for health in fp72

Collaborative researchfor Health in FP7

2:Translating research for human health

Integrating biological data and processes: large-scale data gathering, systems biology

Research on the brain and related diseases, human development and ageing

Translational research in major infectious diseases: to confront major threats to public health antimicrobial drug resistance, HIV/AIDS, malaria and TB, emerging epidemics, neglected infectious diseases

Translational research in other major diseases: cancer, cardiovascular disease, diabetes and obesity, rare diseases, and other chronic diseases


Collaborative research for health in fp73

Collaborative researchfor Health in FP7

3:Optimising the delivery of health care

Enhanced health promotion and disease prevention (providing evidence of best public health measures – life styles, interventions, special focus on mental health, etc.)

Translating clinical research into clinical practice (patient safety, better use of medicines, benchmarking, pharmacovigilance, etc.)

Quality, solidarity and sustainability of health systems (organisational and financial aspects, health systems, etc.)


Collaborative research for health in fp74

Collaborative researchfor Health in FP7

Two other issues will be addressed across all activities:

Child health

The health of the ageing population

For more information see Specific programme:

http://cordis.europa.eu/fp7/spe_programmes.htm


Collaborative research for health in fp75

Collaborative researchfor Health in FP7

Special encouragement and measures for:

SMEs

Participation of SMEs and larger companies in all areas

Special topics for SMEs

International Cooperation

Participation possible in all areas

Special International Cooperation Actions (SICA)


Translational sciences dialog among basic and clinical scientists

Translational sciences Dialog among basic and clinical scientists

Clinical research

  • Forward Translation:

  • Use bioinformatics, functional genomics into clinical practice

  • Develop biomarkers & molecular imaging techniques at early stage of target validation

Phase I – II – III

studies

In vitro studies

  • Reverse Translation:

  • Validating the biochemistry in target & biomarker discovery

  • Bring measurements from the clinic into earlier stages of basic research

Animal models

Target validation

Basic research


Collaborative research for health in fp76

Collaborative researchfor Health in FP7

SUMMARY

Continuity in collaborative Health research to:

develop new tools and technologies

promote translational research

enhanced efforts to optimise delivery of health care

[ using usual FP funding and coordination mechanisms ]

&

A novel approach to improve drug development:

The Innovative Medicines Initiative

[ using the proposed Joint Technology Initiative in FP7 ]


Research funding schemes in fp7

Research fundingschemes in FP7

Funding instruments proposed:

Collaborative projects to develop new knowledge, new technology, products, demonstration activities

Small or medium-sized focused research actions

Large-scale integrating projects

Projects targeted at special groups (eg SMEs or International)

Networks of Excellence

Coordination and support actions

Support for investigator driven research by individual teams (ERC)

Support for training and career development of researchers

Research for the benefit of specific groups (in particular SMEs)


Basic principles of evaluation and funding

Annual calls for proposals, with topics set by the EC (following consultation and approval by Member States).

Proposals evaluated by panels of independent experts (being an expert for the EC is a valuable experience)

Criteria and thresholds

Proposals short-listed for funding (with recommendations)

Consortia receive EC funding for R&D tasks (shared cost)and for project management

12- of 18-month reports and reviews

Basic principles of evaluation and funding


Collaborative research for health in fp77

Collaborative researchfor Health in FP7

  • Next steps:

  • Approval by Council and European Parliament

  • Preparation of work programmes for years 1 & 2.

    • Currently consulting Member and Associated States (PC)

  • First calls for proposals: Dec. 2006 (tbc)

    • first deadline end-March ’07 (tbc)

    • second deadline end-June ’07 (tbc)

  • [ not all areas will be open at in each call ]


Information on fp7

EU research:

http://europa.eu.int/comm/research

Seventh Framework Programme:

http://europa.eu.int/comm/research/future/index_en.cfm

Information on research programmes and projects:

http://www.cordis.lu

RTD info magazine:

http://europa.eu.int/comm/research/rtdinfo

Innovative Medicines Initiative

http://europa.eu.int/comm/research/imi.html

Information requests:

[email protected]

Information on FP7

[email protected]


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