Principles of New Animal Drug Effectiveness: An Overview. Linda M. Wilmot, DVM, MS Director Division of Production Drugs. Why do we test for animal drug effectiveness?.
Linda M. Wilmot, DVM, MS
Division of Production Drugs
On the other hand, the body of evidence to
support effectiveness may be a patchwork of
one or more of these studies.
These studies can come from
“Key characteristics of a systematic review are a clearly stated set of objectives with predefined eligibility criteria for studies; an explicit, reproducible methodology; a systematic search that attempts to identify all studies that meet the eligibility criteria; an assessment of the validity of the findings of the included studies (e.g., through the assessment of risk of bias); and a systematic presentation and synthesis of the attributes and findings from the studies used.”*
*Lean, J, Rabiee, AR, Duffield, TF, et al. Invitedreview: use of meta-analysis in animal health and reproduction: methods and applications. J Dairy Sci 2009;92:3545-65.Control Over Non-Traditional Studies
Confidence with which the data relating to effectiveness of a new animal drug for an intended use under the conditions tested can be used to conclude that the new animal drug will be effective in the target animal population for the intended use and associated conditions of use suggested in the labeling.
The results obtained from a study are likely to be repeatable.