Sponsored Links
This presentation is the property of its rightful owner.
1 / 20

# Στατιστική διαγνωστικών δοκιμασιών PowerPoint PPT Presentation

Στατιστική διαγνωστικών δοκιμασιών. Καμπύλη ROC. Διαγνωστικός έλεγχος. Οι ιατρικοί διαγνωστικοί έλεγχοι έχουν τρεις στόχους: Να δώσουν αξιόπιστες πληροφορίες για την κατάσταση ενός ασθενούς Να επηρεάσουν το πλάνο αντιμετώπισης της ασθένειας.

### Download Presentation

Στατιστική διαγνωστικών δοκιμασιών

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.

- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

#### Presentation Transcript

ROC

• :

• .

• .

• .

• . (-).

• ( )

• (..PSA, )

• (.. -V)

• (/, .. CRP )

• ()

• (/)

• : ;

• PPV=TP/TP+FP

• :

• ;

• NPV = TN/F+TN

PPV=TP/TP+FP = 14/22 = 0.6464%

Prev = 15/114 = 13%

NPV = TN/F+TN = 91/92 = 0.9999%

• Bibbo N. et al. Acta Cytol 1988

• Prev = 13%

• Sens = 93%

• Spec = 92%

• PPV = 64%

• NPV = 99%

• Prev = 38%

• Sens = 93%

• Spec = 92%

• PPV = 88%

• NPV = 96%

### PPV & NPV

• :

• Sens = TP/TP+FN

• :

• Spec = /FP+TN

Sens = TP/TP+FN = 14/15 = 0.93 93%

Spec = /FP+TN = 91/99 = 0.92 92%

• Bibbo N. et al. Acta Cytol 1988 (Book: Medical Epidemiology)

: 100%

:100%

### (LR)

• LR+

LR+=Sens/(1-Spec) (0, )

LR+=1

LR+ > 1( )

• LR-

LR-= (1-Sens)/Spec (0, )

LR-=1

LR- < 1 ( )

### A I

• = TP=0,82

• 1-= FN=0,18

• E= TN=0,77

• 1-= FP=0,23

• LR=TP/TN= 0,82/(1-0,77)=3,56

• SEp(1-p)/n

• Width SE*1,96

• E;

• 70,6%- 93,4%

• 69%-85%

• 6,6%-29%

• 15%-31%

### ROC

• UC

• 0.5 <AUC < 1.0

• AUC=0.5 ( )