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Β Oxidation

↑ FFA. Β Oxidation. TCA Cycle. ↑Electron Donors. NAD +. ↑ NADH+H +. ↑ O 2 -. ↑FADH 2. FAD. Complex I. e -. Complex IV. e -. Complex II. Q -. Complex III. e -. e -. Electron Transport Chain. EXERCISE IMPROVES ENDOTHELIAL FUNCTION. Hamby et al, Diabetes Care 26:2119-2125, 2003

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Β Oxidation

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  1. ↑FFA Β Oxidation TCA Cycle ↑Electron Donors NAD+ ↑ NADH+H+ ↑ O2- ↑FADH2 FAD Complex I e- Complex IV e- Complex II Q- Complex III e- e- Electron Transport Chain

  2. EXERCISE IMPROVES ENDOTHELIAL FUNCTION Hamby et al, Diabetes Care 26:2119-2125, 2003 Watts, et al, Journal Pediatrics 144:620-625, 2004 Walsh, et al, JAP 95:20-25, 2003

  3. NITRIC OXIDE Eight weeks of training in healthy adults i Maeda, et al. Life Sciences 69:1005-1016, 2001

  4. Padilla, et al., European Journal of Applied Physiology, 98:256-262, 2006

  5. Padilla, et al. Medicine and Science in Sport and Exercise, in press.

  6. Fly, et al. Medicine and Science in Sport and Exercise, in press.

  7. Padilla, et al. Medicine and Science in Sport and Exercise, in press.

  8. Active & Inactive Overweight Men Treadmill Exercise FMD Response Harris, et al, Obesity, 2008

  9. Habitual Physical Activity Single Physical Activity Session Oxidative Source Antioxidant Defense (SOD) Anti-inflammatory Myokine ( IL-6)  Oxidative Stress ( 8 PG F2alpha) Inflammatory Stress ( TNF-alpha) Visceral Fat ( TNF-alpha) Insulin Resistance  NO bioavailability Systemic Inflammation ( CRP)  Blood Flow  Endothelial Function Insulin Resistance

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