Focused Ultrasound: a New Evidence of Modulation of Neurotransmitters in CNS. Seung-Schik Yoo, Ph.D., M.B.A. Tissue Imaging/Engineering Laboratory Dept. of Radiology, Brigham and Women’s Hospital, Harvard Medical School (USA). Non-invasive Direct Neuromodulation. 1. 2. 3.
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Seung-Schik Yoo, Ph.D., M.B.A.
Tissue Imaging/Engineering Laboratory
Dept. of Radiology, Brigham and Women’s Hospital,
Harvard Medical School (USA)
Limitations of current neuromodulation technique
Adapted from Hoy and Fitzgerald, Nature Review/Neurology, 2010
Gavrilov, et al. 1985
Focused ultrasound can provide a new means for non-invasive, localized functional neuro-modulation.
Bi-modal modes of modulation, i.e. excitation and suppression, are possible.
FUS also changes the level of neurotransmitters, with potential implication in the treatment of psychiatric disorders.