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A. TLR4 deficiency. Gja1. Hmga1. Timp2. Ereg. Areg. Spp1. Hbegf. Ran. Tnc. EGFR family. Myc. Mina. Cell growth & cell cycle. Promotion of adenoma development. Spp1. Pf4. Cxcl5. Cxcl11. B. TLR4 deficiency. Cxcl9. Ccr1. Chst1. MCP-1. Enpp2. MCP-1. S100a8. Cxcl2.

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  1. A. TLR4 deficiency Gja1 Hmga1 Timp2 Ereg Areg Spp1 Hbegf Ran Tnc EGFR family Myc Mina Cell growth & cell cycle Promotion of adenoma development Spp1 Pf4 Cxcl5 Cxcl11 B. TLR4 deficiency Cxcl9 Ccr1 Chst1 MCP-1 Enpp2 MCP-1 S100a8 Cxcl2 Kng1 Ccr2** Ccl5* Inflammatory Response TLR4 sufficiency Spp1 Chemotaxis Utrn Il1rn Tumor growth and progression Ereg Pthlh Arg1 Odc1 EGFR signaling Cell proliferation Genes increased in BALBLpsd 1 day following chronic BHT Genes decreased in BALBLpsd 1 day following chronic BHT Genes increased in BALB 1 day following chronic BHT Genes increased in BALBLpsd tumors Genes decreased in BALB tumors Genes increased in BALB tumors No change in transcript

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