Supplementary fig 1
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a. b. 120. T47D. 100. 80. % Cell migration. 60. *. 40. 20. 0. Vector. S100A7. SCP6. % Cell migration. *. Supplementary Fig. 1. T47D. 30. Vector S100A7. 20. % Invasion. *. 10. *. 0. -EGF +EGF. Supplementary Fig. 2. EGF. EGFR. LIMK-1/2.

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Supplementary Fig. 1

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Supplementary fig 1

a

b

120

T47D

100

80

% Cell migration

60

*

40

20

0

Vector

S100A7

SCP6

% Cell migration

*

Supplementary Fig. 1


Supplementary fig 1

T47D

30

Vector

S100A7

20

% Invasion

*

10

*

0

-EGF +EGF

Supplementary Fig. 2


Supplementary fig 1

EGF

EGFR

LIMK-1/2

Active Rac-1

GTP

S100A7-ERα-

Migration

p-Cofilin

F-actin

G-actin

N

p-p65-NF-KB

ATP

NF-KB binding site

S100A7-ERα+

MMP-9

Invasion

LIMK-1/2

MMP-9

Active Rac-1

MMP-9

Invasion

Migration

Supplementary Fig. 3


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