1 / 29

CARCINOGENUS FOODS

nusa
Download Presentation

CARCINOGENUS FOODS

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

    2. ???? ???? ??? ???? ???? ???? ?? ?? ??? ???? ?? ???? ??? ???? ????? ??? ?? ?? ?? ??? ????? ??? ?? ??? ??????

    3. CARCINOGENIC FOODS MOHAMED H. EL-SAEID, Ph.D. Elsaeidm@ksu.edu.sa

    4. FOODS IS A FACT ? FOODS FOR LIFE ? HEALTHY FOODS Wholesome @ Fresh - Processed ? FOODS CUSE CANCER ? *Fresh *Contaminated > Pesticides…etc *Processed >>>>>>

    5. PROCEESED FOODS ? DRIVE TO CANCER. * Barbecued & Smoked Foods ? BENZO(a)PYRENE * Carbohydrate Rich foods ? ACRYLAMIDE >>>>

    6. ACRYLAMIDE(AA) - One of PAHs - MW: 71.1 - MP: 85 °C - BP: 125 °C - WS: 2150 g/l at 30 °C -CAS # 79-06-1 H2C=CH—C=O / H2N

    7. AA FACTS ? Poly AA was used in Agric., Water & Sugar. ? Many long-term exposure studies reported AA as a * Reproductive toxicity * Embryotoxicity * Teratogenicity * Mutagenicity * Carcnigensity ? AA was a serious problem in drinking Water (MAL 1 µg/l by WHO) ? April 2002 Swedish National Food Authority & Stockholm Univ. found high levels of AA in high starch foods * Probable human carcinogen. * Neurotoxicant. * DNA damage.

    8. >>>> ? US EPA, FDA, WHO, FAO, EUHC, ACSH, SNFA, IARC, & CSPI report there is link seen between cooked carbohydrate foods & CANCER during Maillard reaction. ? MAL was set at 1 µg/l or g. ? MAL was set at 0.5 µg/l (WHO). ? NOAEL 0.2 mg/kg bodyweight. ? New Zealand National Nutrition Survey found 0.3 mg/kg bodyweight.

    9. AA FORMATION MECHANISM ? Amino Acids/Reducing Sugars (Maillard reaction ? Schiff base ? De COOH ) Such as Asparagine and D-Glucose. ? Oils/Nitrogen (Thermal degradation of glycerol ? Oxidation of acrolin to acrylic acid ? react with Ammonia ?Pyrolysis) ? Depolymerization of PolyAA.

    11. H2C=CH—HC=O Acrolein ? H2C=CH—C=O Acrylic A. / OH ? ? H2C=CH—C=O AA / H2N

    12. ANALYSIS METHODS

    13. EXTRACTION ? SPE ?Recovery % 86.7 ? ASE ? Recovery % 97.4 ? SFE ? Recovery % 96.7

    14. AA RESULTS LC/MS/MS. AA LEVELS SAMPLE SIZE AA LEVELS IN French Fries TIME & COLOR EFFECT French Fries LESS AA OUR AA

    15. LC/MS/MS

    16. >>>>RT 2.4 min.

    17. AA LEVELS

    18. AMINO As. / D-GLUCOSE EFFECT. Amino A. AA(ppb) Aspar.+ D-Glucose 9270 Aspar. 117 Ala., Arg., Aspart., Lys., Cyste. + D-Glucose 50

    19. TEMP. / TIME EFFECT. FF Temp./Time AA(ppb) 160 °C / 4 min. 27 170 °C / 4 min. 70 180 °C / 4min. 227 160 °C / 4.5 min. 326 160 °C / 4 min. 973

    20. SAMPLE SIZE *1 gram sample Bread (4) 63 ppb Cereal (4) 217 ppb Coffee (4) 127 ppb Potato Chips (4) 613 ppb *4 gram sample Bread Crumbs (3) 65 ppb Cereal (3) 214 ppb Coffee (3) 115 ppb Potato Chips (3) 597 ppb

    21. AA LEVELS IN French Fries

    22. TIME & COLOR EFFECT

    23. OUR AA (ppb)

    26. And More >>>> * Baqlawa * Sham balah * Konafa * Samosak * Metabaq * Kobiba * Judge sweet * Shapora >>>>>>>>

    27. French Fries LESS AA

    28. RECOM. Consumption decrease > Children,,,Hum Enzyme-Catalyzed Hydrolysis in the Soil Non biological Hydro. In H2O Prevent AA formation > FDA Look and Share >>>Joint Inst.for Food Safety & Appl. Nutrition (JIFSAN) & National Center for Food Safety & Tech. (NCFST) >>>>>

    29. >>>> >> Data base >> More research about AA formation >> Decrease AA formation by PH, Temp., Time, H2o cont., Aspr.cont. >> Breading and Genetic Eng. For les Aspr. >> UV and or Radiation. >> React Aspr. With SH group >> Food treatments.>> AA Polymerization or Enzyme-Catalyzed Hydrolysis.

    30. ????? ??? ????? ??? ???? ???????? ?????

More Related