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EDEN Integrated Project proposal Emerging Diseases in a changing European Environment. Florence Putterman. FP6 call

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EDEN Integrated Project proposal Emerging Diseases in a changing European Environment

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Eden integrated project proposal emerging diseases in a changing european environment

EDEN Integrated Project proposal

Emerging Diseases in a changing European Environment

Florence Putterman


Eden integrated project proposal emerging diseases in a changing european environment

FP6 call

“The aim is to identify, evaluate and catalogue European ecosystems and environmental conditions linked to global change, which can influence the spatial and temporal distribution and dynamics of pathogenic agents.

A co-ordinated European approach is needed to provide predictive emergence and spread models including global and regional prevention, early warning, surveillance, and monitoring tools and scenarios.

Co-ordination with international organizations and third world countries is essential.”


Eden integrated project proposal emerging diseases in a changing european environment

Keywords

Coordinated European approach

  • The aim is to

    • identify, evaluate andcatalogue

  • European

    • ecosystems andenvironmental conditions

  • linked to global change and which can influence

    • the spatial distribution the temporal distribution and the dynamics

  • of pathogenic agents.

  • Predictive emergeance and spread models including the following tools and scenarios:

  • Global and Regional prevention

  • Early warning

  • Surveillance

  • Monitoring

Coordination with international organisations and third world countries.


Eden integrated project proposal emerging diseases in a changing european environment

PUB/HEALTH & SOCIO ECONOMY

AGRO/ECOLOGY

Ecosystème

Regional/local developpment

landscapes

economical / social conditions

FOCI

Climat

Human activities

Vectors

hosts

Pathogens

PATHOGENIC CYCLE


Eden integrated project proposal emerging diseases in a changing european environment

‘‘indicator diseases’’

  • Tick-borne Disease–diseases already present in Europe that have shown significant recent increases in incidence, at least partly due to changes in human behaviour in relation to the environment.

  • Rodent-borne viruses (hanta, arena, cowpox) – widespread but under-reported diseases within Europe, with strong links with habitat and landscape structures.

  • Leishmanioses– persistent on the southern fringes of Europe and beyond (southern Mediterranean basin), with the potential to expand as environments change.

  • West Nile Virus –periodic and occasionally severe local outbreaks, especially on the eastern fringes of Europe, currently showing strong associations with landscape patterns.

  • Malaria – an ancient scourge of Europe, currently now on her southern and eastern fringes, with the potential for re-emergence following environmental changes.

  • Maladies Africaines – new strains of West Nile Virus and new diseases such as Rift Valley Fever may be introduced to Europe from tropical regions linked by bird and other (e.g. traded livestock) migratory routes to Europe.


Eden integrated project proposal emerging diseases in a changing european environment

A common approach for all Sub-Projects


Eden integrated project proposal emerging diseases in a changing european environment

Rodent borne diseases

Tick borne diseases

West Nile Virus

African Platform

Leishmaniasis

Malaria


Eden integrated project proposal emerging diseases in a changing european environment

Rodent borne diseases

Tick borne diseases

West Nile Virus

Disease Modelling

Data Management

LR Spatial Modelling

Environmental Change

Biodiversity

African Platform

Leishmaniasis

Malaria


Eden integrated project proposal emerging diseases in a changing european environment

Ecosystem components

studies

WP1: Landscape, habitat, climate

Malaria

Tick

borne

Rodent

borne

Leishmania

West Nile

Africa

Platform

WP2: Vector

Pattern

Process

WP3: Public Health

Pattern

Process

WP4: Animal Reservoir

Pattern

Process

WP5: Individual disease Data management

& Modelling

Pattern

Process


Eden integrated project proposal emerging diseases in a changing european environment

Data management & information systems

Low resolution spatial modeling

Disease transmission

modeling

Environmental

change monitoring

Biodiversity

Ecosystem components

studies

Horizontal integration

WP1: Landscape, habitat, climate

Malaria

Tick

borne

Rodent

borne

Leishmania

West Nile

Africa

Platform

WP2: Vector

WP6 Horizontal

activities

Pattern

Process

WP3: Public Health

WP6.1 Data

management

Pattern

Process

WP4: Animal Reservoir

WP6.2 RS tools

Pattern

Process

WP5: Individual disease Data management

& Modelling

WP6.3

PhD program

Pattern

Process


Eden integrated project proposal emerging diseases in a changing european environment

Data management & information systems

Low resolution spatial modeling

Disease transmission

modeling

Environmental

change monitoring

Biodiversity

Ecosystem components

studies

Emergence

& spread models

Horizontal integration

WP1: Landscape, habitat, climate

Malaria

Tick

borne

Rodent

borne

Leishmania

West Nile

Africa

Platform

WP2: Vector

WP6 Horizontal

activities

Pattern

Process

WP3: Public Health

WP6.1 Data

management

WP7

Overall

Integration:

Tools

&

scenarios

Pattern

Process

WP4: Animal Reservoir

WP6.2 RS tools

Pattern

Process

WP5: Individual disease Data management

& Modelling

WP6.3

PhD program

Pattern

Process


Eden integrated project proposal emerging diseases in a changing european environment

Data management & information systems

Low resolution spatial modeling

Disease transmission

modeling

Environmental

change monitoring

Biodiversity

Ecosystem components

studies

Emergence

& spread models

Horizontal integration

WP1: Landscape, habitat, climate

Malaria

Tick

borne

Rodent

borne

Leishmania

West Nile

Africa

Platform

WP2: Vector

WP6 Horizontal

activities

Pattern

Process

WP3: Public Health

WP6.1 Data

management

WP7

Overall

Integration:

Tools

&

scenarios

Pattern

Process

WP4: Animal Reservoir

WP8: Training, Dissemination, Management & Coordination

WP6.2 RS tools

Pattern

Process

WP5: Individual disease Data management

& Modelling

WP6.3

PhD program

Pattern

Process


Eden integrated project proposal emerging diseases in a changing european environment

Project strategy

HEALTH/ENVIRONMENT RESEARCH

of model diseases in a variety of representative environmental settings

TOOLS and POLICIES

Characterise (new) transmission cycles

Catalogue of ecosystems and environmental conditions at risk: “emerging disease hot-spots”

Identify factors triggering emergence and spread

Develop predictive emergence and spread models

Develop early warning, surveillance and monitoring tools

Identify environmental changes likely to favour emergence

Contribute to decision support and policy making


Eden integrated project proposal emerging diseases in a changing european environment

Project strategy

HEALTH/ENVIRONMENT RESEARCH

of model diseases in a variety of representative environmental settings

TOOLS and POLICIES

Characterise (new) transmission cycles

Catalogue of ecosystems and environmental conditions at risk: “emerging disease hot-spots”

EDEN strategy document

integrated ‘trans-disciplinary’ health/environment approach.

Identify factors triggering emergence and spread

Develop predictive emergence and spread models

Develop early warning, surveillance and monitoring tools

Identify environmental changes likely to favour emergence

Contribute to decision support and policy making


Eden integrated project proposal emerging diseases in a changing european environment

EDEN strategy document

A key deliverableproduced by the Steering Committee and with back-up from the advisory group, specialists with internationally recognised skills in (i) biodiversity monitoring and assessment, (ii) environmental change detection, (iii) disease modelling, remote sensing, image processing and interpretation, and (iv) public health.

The EDEN strategy document will propose an innovative integrated ‘trans-disciplinary’ health/environment approach for the unified analysis of the various EDEN outputs. The development of such an approach will be a major breakthrough of EDEN.


Eden integrated project proposal emerging diseases in a changing european environment

1

2

3

4

5

Objectives timeframe

SD

H&E

T&P

Dissemination

SD: EDEN Strategy document

H&E: Health/Environment research

T&P: Tools and policies


Eden integrated project proposal emerging diseases in a changing european environment

External

sources

EDEN Indicator

Diseases

Individual diseases models

EDEN Steering Committee

Advisory

group

integrated models health-environment

DMEWS

Disease Monitoring & Early Warning Systems

Knowledge Flow


Eden integrated project proposal emerging diseases in a changing european environment

conclusion

Annex1, chap 4.1 Contribution to the objectives of the sub-priority

“EDEN’s bold ambition is to enable a multi-DMEWS system on a solid scientific foundation running from the theoretical understanding of the reasons for the emergence of new diseases in vulnerable ecosystems, through an understanding of complex disease dynamics, to the practical application of such knowledge to disease control.

We do not know the precise shape of this future yet: EDEN presents a chance to Europe to invest in some of the ‘brightest and best’ researchers to ensure success with this vision, and in doing so to advance significantly the state-of-the-art and put Europe firmly at the forefront of DMEWS.”


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