Guidelines for nhanes research proposal submission
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Guidelines for NHANES Research Proposal Submission. by Natalie Dupree Margaret McDowell. Objectives . To provide a brief overview of NHANES To describe the planning process for NHANES 2005-2006 To provide collaborators with information about the research proposal preparation process.

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Guidelines for NHANES Research Proposal Submission

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Guidelines for NHANES Research Proposal Submission

by

Natalie Dupree

Margaret McDowell


Objectives

  • To provide a brief overview of NHANES

  • To describe the planning process for NHANES 2005-2006

  • To provide collaborators with information about the research proposal preparation process


Goals of NHANES

  • Study the relationship of diet, nutrition and health

  • Explore emerging public health issues

  • Establish a national probability sample of genetic material for future research


NHANES sample design

  • Continuous data collection beginning in 1999

  • Multi-stage probability sample

  • Annual national sample of 7,000 interviewed and 5,000 examined persons

  • Estimates of population subgroups require two or more years of data


NCHS NHANES Program Staff

  • Planning Branch

  • Operations Branch

  • Information Management Branch

  • Analysis Branch


Planning Branch Activities

  • Review current survey content

  • Coordinate NHANES Research Consortium activities

  • Prepare proposal guidelines

  • Solicit proposals

  • Coordinate review and evaluation of proposals

  • Decisions


Considerations for topic selection and inclusion

  • Safe, non-invasive procedures

  • Proven methodology

  • Prevalence of 5% or more

  • Feasible in NHANES environment

  • Funding available


Proposal evaluation criteria

  • Methods clearly stated

  • Public health significance documented

  • Participant burden

  • Data uses outlined

  • Target group(s) identified

  • Data relevant across other NHANES topics

  • Confidentiality and disclosure issues addressed


Analytic issues related to planning survey content

  • Cross-sectional design w/capability for longitudinal follow-up

  • Validated methods and data collection instruments used.

  • Ideally, a link between interview and examination content

  • Minimum 2-year data collection cycle


Examples of Proposal Topics

  • New questionnaire content

  • Modify existing questionnaire content

  • New examination component (e.g., nasal swab, dermatology exam)

  • Lab analyte


What is the collaborator’s role in the survey planning process?

  • Subject matter expertise and technical support

  • QA/QC evaluation of data during collection

  • Participation in NHANES field staff training

  • Funding support


Confidentiality and subject protection issues

  • Assurances for privacy, confidentiality,and safety of subjects

  • Institutional Review Board (IRB) approval of protocol and survey materials

  • Office of Management and Budget (OMB) approval- especially respondent burden issues


NHANES 2005-2006 planning timelines

  • Pilot testing (if needed): 1+ years prior to data collection

  • Synchronize w/survey’s 2 year data collection cycles (’05-’06, ’07-’08, etc.)

  • MEC configuration lead time

  • Survey information system and database preparation: ~6 months lead time


Research Proposal Guidelines for NHANES 2005-2006

  • Letter of Intent

  • Initial NHANES Program response

  • Full proposal submission

  • Evaluation panel review


Letter of intent

  • Name of project

  • Statement of public health significance

  • Target age/gender group(s)

  • Research objectives

  • Summary of methodology

  • Questionnaire vs. exam

    • If questions – where to administer


Estimating Costs

  • Questionnaires: Guidelines provided (cost per minute, cost to modify CAPI)

  • Examination costs: Exam time, staff time, per sample domain

  • Data processing and preparation costs

  • CDC costs

  • NHANES Survey Costs: sampling, instrumentation, training, and reporting


NHANES Resources and points of contact

  • NHANES website

  • NHANES proposal guidelines and planning documents

  • Evaluation criteria

  • NHANES Listserv

  • NHANES Consortium


NHANES Website

  • Overview of NHANES

  • Questionnaires and survey components

  • Data products and reports

  • MEC virtual tour

  • NHANES 2005-2006 guidelines (future posting)


Summary

  • Learn about the Survey

  • Follow guidelines and instructions

  • Select appropriate topics and target groups

  • Link interview and exam components

  • Identify funding

  • Address human subjects issues


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