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Calcium binding proteins

Calcium binding proteins. Maria Tereshina Vsevolod Belousov. Calcium binding protein CaBP2 Results of CD search by BLAST reveal two Efh domains. Calcium binding protein CaBP2 Results of CD search by BLAST reveal two Efh domains, each consisting of ef-hand motifs.

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Calcium binding proteins

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  1. Calcium binding proteins Maria Tereshina Vsevolod Belousov

  2. Calcium binding protein CaBP2 Results of CD search by BLAST reveal two Efh domains

  3. Calcium binding protein CaBP2 Results of CD search by BLAST reveal two Efh domains, each consisting of ef-hand motifs

  4. Stricture of typical ef-hand containing protein, calmodulin

  5. Stricture of typical ef-hand containing protein, calmodulin +4Ca2+

  6. N-terminal domain of calmodulin with bound Ca2+ Yellow- key positions in ef-hand, coordinating Ca2+ (usually Asp & Glu)

  7. N-terminal domain of calmodulin with bound Ca2+ N-terminal domain of calmodulin with bound Ca2+ Yellow- key positions in ef-hand, coordinating Ca2+ (usually Asp & Glu)

  8. Calsequestrin- ER protein with negatively charged surface that binds Ca2+ with low affinity

  9. Crystal structure of calsequestrin. Red spacefill- Asp & Glu residues

  10. C2 domains- Ca2+-dependent lipid binding folds

  11. Structure of C2 domain from PKCa Yellow- Asp residues coordinating Ca2+

  12. Novel Ca2+ binding domain in bacterial collagenases

  13. Structure of Ca2+-binding domain of collagenase Conformation changes upon Ca2+ load

  14. Structure of Ca2+-binding domain of collagenase Conformation changes upon Ca2+ load

  15. CONCLUSION The diversity of calcium binding proteins is great!

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