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Activated protein-C

Propagation FXIa. Platelets. Activated protein-C. IXa/VIIIa. Thrombin activated fibrinolysis inhibitor. FVIIa/TF initiation. FXa/Va. Fibrinolysis. Factor XIIIa. Fibrinogen. Fibrin. Coagulation cascade: Central role of thrombin. VBWG. Reactivation of coagulation cascade.

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Activated protein-C

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  1. Propagation FXIa Platelets Activatedprotein-C IXa/VIIIa Thrombin activatedfibrinolysis inhibitor FVIIa/TF initiation FXa/Va Fibrinolysis FactorXIIIa Fibrinogen Fibrin Coagulation cascade: Central role of thrombin VBWG Reactivation of coagulation cascade Vessel wall endothelial lining Inhibition of fibrinolysis Thrombin Clot formation and stabilization

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