Aerosol Delivery Devices and Peak Flowmeters. Fritz Merkel , BS, RCP Community Healthworker Training February 2008. Hang in there!. Getting near the end. Hopefully we’ll have a little fun, and Learn something. NAEPP says….blah, blah, blah
Output range is 30-100 ml. 4
Velocity 15 m/s > falls rapidly (0.2 second) 4
80% deposition in oropharynx.
10-15% deposited in in lungs.
Optimal deposition size is < 6 mm (1-5 mm) 5
Propellant chlorofluorocarbon – banned 1987 (exempted under “essential use” ruling) -lose permanent exemption end 2008.MDI
**Candida (thrush)/hoarseness, mouth sore**
(for inhaled steroids only)
- “Parent” must know how to use.
(~ 50% effective)
Gamma scan: Beclomethasone (BDP)-healthy subject Right: BDP with HFA propellant = greater lung deposition & less oropharygeal deposition than CFC propellant. 9 (no spacer)
E Z Spacer
(But so are MDI’s)
Lung Deposition (various studies) between traditional and newer devices. hydrofluroalkane-beclomethasone, small volume neb, dry powder inhaler. 40-50% possible now vs. 10-15% 16
(propellant free, spring driven “MDI” - Boehringer Ingelheim)
Breath-actuated, multi-dose cassette, battery-powered inhalation assist12