Technology transfer with the u s army medical research and materiel command l.jpg
This presentation is the property of its rightful owner.
Sponsored Links
1 / 26

Technology Transfer with the U.S. Army Medical Research and Materiel Command PowerPoint PPT Presentation


  • 136 Views
  • Uploaded on
  • Presentation posted in: General

Technology Transfer with the U.S. Army Medical Research and Materiel Command. Paul C. Mele, Ph.D. Director Office of Research and Technology Applications USAMRMC. USAMRMC. Headquartered at Fort Detrick, MD The R&D arm of the Army Medical Command Army’s medical materiel developer

Download Presentation

Technology Transfer with the U.S. Army Medical Research and Materiel Command

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Technology transfer with the u s army medical research and materiel command l.jpg

Technology Transfer with the U.S. Army Medical Research and Materiel Command

Paul C. Mele, Ph.D.

Director

Office of Research and Technology Applications

USAMRMC

Mid-Atlantic FLC October 24, 2007


Usamrmc l.jpg

USAMRMC

  • Headquartered at Fort Detrick, MD

  • The R&D arm of the Army Medical Command

  • Army’s medical materiel developer

  • ~$2 billion funding in FY 2007

Mid-Atlantic FLC October 24, 2007


Mrmc mission l.jpg

MRMC Mission

  • To provide medical materiel to sustain the health, well being and military readiness of U.S service men and women:

    - drugs

    - vaccines

    - devices

    - medical IT

  • Basic research, Advanced development, Final Product

Mid-Atlantic FLC October 24, 2007


Medical r d programs l.jpg

Medical R&D Programs

  • Infectious Diseases

  • Casualty Care

  • Operational Medicine

  • Chemical & Biological Defense

  • Telemedicine and Medical IT

  • Congressional Research Programs

Mid-Atlantic FLC October 24, 2007


Mrmc laboratories l.jpg

MRMC Laboratories

  • Institute of Infectious Diseases (USAMRIID)

    biodefense – Fort Detrick

  • Telemedicine and Advanced Technology Research (TATRC)

    medical IT , simulations, telemedicine – Fort Detrick

  • Center for Environmental Health Research (USACEHR)

    environmental toxicology and monitoring – Fort Detrick

  • Medical Materiel Development Activity (USAMMDA)

    advanced development, clinical trials – Fort Detrick

Mid-Atlantic FLC October 24, 2007


Mrmc laboratories6 l.jpg

MRMC Laboratories

  • Walter Reed Army Institute of Research (WRAIR)

    infectious diseases, neuroscience, trauma – Silver Spring, MD

  • Institute of Chemical Defense (USAMRICD)

    chemical defense - Edgewood, MD

  • Aeromedical Research Laboratory (USAARL)

    aviation medicine, human interface - Fort Rucker, AL

  • Institute of Environmental Medicine (USARIEM)

    performance, exercise physiology, sports medicine - Natick, MA

  • Institute of Surgical Research (USAISR)

    trauma, emergency medicine – San Antonio, TX

Mid-Atlantic FLC October 24, 2007


Facilities operations l.jpg

Facilities & Operations

  • Worldwide research laboratories

  • GMP pilot plant

  • Clinical trials

  • Regulatory experience: FDA & EPA

  • BL-3 & BL-4 laboratories

  • Bioinformatics

  • Sleep ward

  • Burn ward

  • Helicopters & flight simulator

Mid-Atlantic FLC October 24, 2007


Technology transfer instruments l.jpg

Technology Transfer Instruments

  • Cooperative Research and Development Agreements (CRADAs)

  • Material transfer agreements

  • Patent license agreements

  • Clinical trial agreements

  • Test and evaluation agreements (“work for hire”)

  • Educational partnerships

  • Partnership Intermediaries

  • Grants, contracts, cooperative agreements, SBIR

Mid-Atlantic FLC October 24, 2007


Marketing efforts l.jpg

Marketing Efforts

  • Federal Register

  • Web pages

    • MRMC & laboratories

    • https://technologytransfer.detrick.army.mil

    • Federal Laboratory Consortium (FLC)

  • Shows & exhibits

  • Third party

  • Direct mailings

  • Internet technology exchanges

  • MRMC scientists

Mid-Atlantic FLC October 24, 2007


Dod technology transfer web site l.jpg

DoD Technology Transfer Web Site

Mid-Atlantic FLC October 24, 2007


Lead partnership intermediary l.jpg

Lead Partnership Intermediary

Mid-Atlantic FLC October 24, 2007


Fort detrick technology transfer initiative l.jpg

Fort Detrick Technology Transfer Initiative

Collaboration between TEDCO and MRMC to promote technology transfer

Congressional funding - $50,000 seed grants for collaborations with MRMC

FY2008 - $750,000 for grants

Partners:

Fort Detrick Business Development Office (FDBDO)

Frederick County Office of Economic Development (FCOED)

Frederick Innovative Technology Center, Inc. (FITCI)

Mid-Atlantic FLC October 24, 2007


Patent license agreements l.jpg

VACCINES

- Japanese encephalitis

- dengue

- anthrax

- Ebola

- Marburg

THERAPEUTICS

- topical skin protectant

- anthrax

- anti-infectives

DEVICES

- absorbable surgical glue

- water bio-monitor

- chemical weapons decon

- critical care platform for litters

- medical information system

METHODS & ASSAYS

- prolonged blood storage

- leishmania diagnostic

- ultrasound lysis of blood clots

Patent License Agreements

Mid-Atlantic FLC October 24, 2007


Technology transfer issue federal contractors and cradas l.jpg

Technology Transfer Issue:Federal Contractors and CRADAs

  • Contractor’s Bayh-Dole rights vs.CRADA partner’s rights

  • Inform CRADA partner of contractor involvement

  • Seek to get a waiver from contractor to CRADA data and intellectual property before work starts

Mid-Atlantic FLC October 24, 2007


Technology transfer issue patent license as procurement risks for licensee l.jpg

Technology Transfer Issue:Patent License as Procurement:Risks for Licensee

  • Licensee provides resources for further development

  • Government-use rights may be seen as potential competition

  • No assurance government will purchase product

  • March in rights

  • Government encourages competition

Mid-Atlantic FLC October 24, 2007


Mrmc web sites l.jpg

MRMC Web Sites

  • US Army Medical Research and Materiel Command

    https://mrmc-www.army.mil

  • USAMRMC Technology Transfer

    technologytransfer.detrick.army.mil

  • Fort Detrick Technology Transfer Initiative (TEDCO)

    www.marylandtedco.com

  • USA Medical Research Acquisition Activity

    (purchasing, contracting, SBIR)

    www.usamraa.army.mil

Mid-Atlantic FLC October 24, 2007


Mrmc web sites17 l.jpg

MRMC Web Sites

  • Telemedicine and Advanced Technology Research Center

    (telemedicine and medical IT)

    www.tatrc.org

  • Congressionally Directed Medical Research Programs

    (research grants)

    http://cdmrp.army.mil

  • Fort Detrick Business Development Office

    (information of business opportunities with Fort Detrick)

    www.fdbdo.com

Mid-Atlantic FLC October 24, 2007


Mrmc contacts l.jpg

MRMC Contacts

USAMRMC Office of Research and Technology Applications

  • Paul Mele (301) 619-6664 [email protected]

  • Barry Datlof (301) 619-0033 [email protected]

  • Sara Miller (301) 619-6975 [email protected]

    Fort Detrick Technology Transfer Initiative

  • Ron Kaese (410) 715-4170 [email protected]

Mid-Atlantic FLC October 24, 2007


Some recent usamrmc technologies l.jpg

Some recent USAMRMC technologies:

Mid-Atlantic FLC October 24, 2007


Slide20 l.jpg

SleepWatch®A Management System for Sleep and Performance in the Operational EnvironmentWalter Reed Army Institute of ResearchU.S. Army Medical Research and Materiel Command

Problem

Sleep deprivation:

  • Consequence of sustained operations

  • Disrupts performance and cognition

  • Battlefield mistakes

  • Could not be measured objectively

Solution

  • Patented wrist watch with integrated software: The Sleep Performance Model (SPM)

  • Measures and relates wrist motion to sleep deprivation and decrements in cognitive ability

  • Combines individual sleep records for management of field units

Validation

  • Laboratory testing

  • Battlefield simulation

  • Troop performance

2006 Technology Transfer

  • Successful non-exclusive license to the manufacturer of the Actigraph watch

  • Licensing the Sleep Performance Model to a company for treatment of behavioral disorders

  • An inquiry for licensing SPM in

    sleep disorders

Mid-Atlantic FLC October 24, 2007


Slide21 l.jpg

Caffeinate Supplement Gum

Biomedical Strategies to Sustain Performance in Fatigued Soldiers

MOMRP research focused on strategies to enhance

Soldier alertness and cognitive readiness during continuous operations when moderate sleep loss is a common problem

This research determined the

efficacy of caffeine and provided

guidance on optimal dosage and

methods of administration

The MOMRP’s research

showed that caffeine

supplement gum is an efficient way of enhancing alertness and performance

of soldiers

Mid-Atlantic FLC October 24, 2007


Slide22 l.jpg

Combined Camouflage Face Paint

Contains insect repellent with 8+ hour protection

Reduces near-IR signature (degree of protection against detection by night vision goggles)

Compact has mirror and 5 colors: green, loam, sand, black & white

Stowage in BDU pockets

Easy to apply/easy to remove

NSN 6840-01-493-7334

Ongoing research to provide CCFP in stick dispensers!

2 colors per stick!

Also available without insect repellent for bug-free environment

NSN 6850-01-493-7309

Mid-Atlantic FLC October 24, 2007


Slide23 l.jpg

One-Handed Tourniquet

  • Provides the soldier who has lost the use of one of his/her extremities, a method of self-administration for the control of a severe life-threatening hemorrhage

  • Can be applied with only the use of one hand, and will control severe arterial, or mixed bleeding

  • Highly cost effective (about $5 per unit)

  • Technical and user testing continue to develop additional sizes & additional uses

  • Self, Buddy, and Medic Aid!

Mid-Atlantic FLC October 24, 2007

USAMMDA

U.S. Army Medical Materiel Development Activity


Slide24 l.jpg

Non-Contact Respiration Monitor

  • Breadboard prototype demonstrates how respiration of soldiers in MOPP Gear is monitored, and will signal breathing status to the medic

  • Device will be totally self-contained, and reliable in high noise & vibration environments such as medical evacuation helicopters

Highly useful for mass triage!

  • Initial technical testing was conducted

  • Future plans include integration of the device into Army gas masks

Mid-Atlantic FLC October 24, 2007


Hemorrhage control chitosan bandage l.jpg

Hemorrhage ControlChitosan Bandage

Lightweight; durable; cost effective

Manufactured from a natural product in shrimp shells called chitosan

Saved Lives!

Soldiers WANT it!

Buddy and Medic Aid used by the Warfighter!

Rapid control of Severe external hemorrhage

caused by extreme trauma

FDA Approved

Fielded in OIF and OEF!

Research ongoing for internal use

Mid-Atlantic FLC October 24, 2007


Slide26 l.jpg

Adenovirus Vaccine

  • Vaccine against virus that causes acute respiratory disease common in military recruits

  • Orally administered, enteric-coated live vaccine, very effective from 1971 to 1999

  • Vaccine production ceased in 1996 due to loss of manufacturer; stocks depleted or expired by 1999

  • Several outbreaks since 1999

  • U.S. Army/Barr Laboratories are co-development partners

  • Production facility complete, clinical trials start March 2004

Mid-Atlantic FLC October 24, 2007


  • Login