Ldl c levels in homozygous autosomal dominant hypercholesterolaemia patients
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LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients. 25. 2 null alleles. 20. 1 null allele, 1 defective allele. 2 defective alleles. 15. 10. LDL-c levels (mmol/L). 5. 0. Before lipid-lowering therapy. After lipid-lowering therapy.

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Ldl c levels in homozygous autosomal dominant hypercholesterolaemia patients
LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients

25

2 null alleles

20

1 null allele, 1 defective allele

2 defective alleles

15

10

LDL-c levels (mmol/L)

5

0

Before lipid-lowering therapy

After lipid-lowering therapy

Sjouke et al., Eur Heart J 2014


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