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DAAD-Go8 Collaboration Novel Functionalised Nanoparticles for Application in the Imaging of Cancer

DAAD-Go8 Collaboration Novel Functionalised Nanoparticles for Application in the Imaging of Cancer. Leone Spiccia School of Chemistry Monash University. Holger Stephan Institute of Radiopharmacy Research Centre Dresden-Rossendorf (FZD). Objective of Australian-German Partnership

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DAAD-Go8 Collaboration Novel Functionalised Nanoparticles for Application in the Imaging of Cancer

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  1. DAAD-Go8 Collaboration Novel Functionalised Nanoparticles for Application in the Imaging of Cancer Leone Spiccia School of Chemistry Monash University Holger Stephan Institute of Radiopharmacy Research Centre Dresden-Rossendorf (FZD)

  2. Objective of Australian-German Partnership • Develop improved copper-based radiopharmaceuticals • Develop novel superparamagnetic multi-modality nanoparticles Imaging and therapy of cancer Monash: FZD: Synthesis of novel molecules Characterization of radiopharmaceuticals and nanomaterials

  3. Tumor visualization • Achievements: • Active collaboration established • Development of highly-stable (novel) radiocopper-based peptides for imaging of cancer (joint paper + joint paper in preparation) PICTURE OF DMPTACN + PEPTIDE - NICE ONE ON FZR REPORT FROM MEMORY

  4. Cellular uptake of SP-NP into BT-474 cells TEM of magnetite nanoparticles • Achievements: • Development of superparamagnetic nanoparticles that penetrate into cancer cells (joint paper in preparation)

  5. Achievements: • New projects are emerging - Infrared imaging dyes • Multidisciplinary training for PhD students • Jose Solano, Katrin Jaeger and Alexander Ruffani

  6. Main challenges: • Further enhancing the multidisciplinary training for PhD students • Achieving materials that compete with commercial products • Translation of laboratory developments into clinical trials requires long-lasting collaboration • Securing funding for current projects and for future joint projects: • Ongoing travel funding – these are mid to long term projects • Personnel and maintenance to expand scope of collaboration • Recruitment of high-quality researchers/students • Strategy: • Seek further DAAD support for travel • Explore EU/Australia joint funding opportunities • Target Marie Curie, ARC, NHMRC & other fellowship schemes • Aggressive promotion of our research

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