My Research Work and Clustering. Bernard Chen 2009. Outline. Introduction Experimental Setup Clustering Future Works. Central Dogma of Molecular Biology. Amino Acids, the subunit of proteins. Protein Primary, Secondary, and Tertiary Structure. Protein 3D Structure.
My Research Work and Clustering
Bernard Chen 2009
A relatively small number of functionally or structurally conserved sequence patterns that occurs repeatedly in a group of related proteins.
These biologically significant regions or
residues are usually:
(heme, pyridoxal-phosphate, biotin…)
Fuzzy C-Means Clustering
Information Granule 1
Information Granule M
Final Sequence Motifs Information
Table 1 summary of results obtained by FCM
Wei’s method: 1285968 sec (15 days) * 6 = 7715568 sec (90 days)
Granular Model: 154899 sec + 231720 sec * 6 = 1545219 sec (18 days)
(FCM exe time) (2.7 Days)