Supplementary Figure 3A
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Supplementary Figure 3A. hu_PPARG prom 3 G A C C G C C G C T T G G G G A C C G G G G G A C C G T T C A G C - G A G G G G C G C G C T - - - T 46 ch_PPARG prom 3 G A C C G C C G C G T G G G G A C C G G G G G A C C G T T C A G C - G A G G G G C G C G C T - - - T 46

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Supplementary Figure 3A

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Supplementary figure 3a

Supplementary Figure 3A

hu_PPARG prom 3 G A C C G C C G C T T G G G G A C C G G G G G A C C G T T C A G C - G A G G G G C G C G C T - - - T 46

ch_PPARG prom 3 G A C C G C C G C G T G G G G A C C G G G G G A C C G T T C A G C - G A G G G G C G C G C T - - - T 46

rh_PPARG prom 3 - - - - - - C G C G C G G G G A C C G C G G G A C C G T T C A G C - G A G G G G A G C G C T - - - T 40

mo_Pparg prom 3 G C C A G G T C T C C - - - - - - - - - A G A A C T A C C G C G T T G G G G A C C G C A T T G T G C 41

ra_Pparg prom 3 G C C A G G T C T C C G C A C G G T C C A G A A C T C C C G C G - - G G A G G C C G C A T T G T G T 48

hu_PPARG prom 3 G T A G C - T G G C C A G G C C C T G T G C C C T G A C G C G T T G T G C T G G C C C T A C G C C C 95

ch_PPARG prom 3 G T A G C - T G G C C A G G C C C T G T G C C C T G A C G C G T T G T G C T G G C C C T A C G C C C 95

rh_PPARG prom 3 G G G G C - T G G C C A G G C C C C G T G C C C G G A C G C G T T G T T C T G G C C C T G C G C C C 89

mo_Pparg prom 3 G G A T C C T G G T G A C A G A T T T - A G A G A G G G G C T C G C C A G C A G C C A C C G G T C G 90

ra_Pparg prom 3 G G A T C - T G G T G A C A G T T T T C A G A G A G G G G C T C G C C A G T A G C C A C C G G G T A 97

hu_PPARG prom 3 G G C G G A G G G G C T G G G G A C G G G - G A C T G G G T G C C T C C G T G C C T C C G C G G A T 144

ch_PPARG prom 3 G G C G G A G G G G CTG G G G A C G G G - G A C T G G G T G C C T C C G T G C C T C C G C G G A T 144

rh_PPARG prom 3 G G CG GA G G G A C T G G G G A C G G G - G A C T G G G T T C C T C C G T G C C T C G G C G G A T 138

mo_Pparg prom 3 C C C T G A G G C T C T A G G G G T C G G A G G G T G G G G A G G A G G A T G C G C C C G T G - A T 139

ra_Pparg prom 3 C C C C G A G G C GC T GG G G G T G G - - - - - - G G G G A G G A G G G T G C G C C G G T G - A T 140

hu_PPARG prom 3 G G A G C G C G C A G C C A G G A C C C C C A G C C G C A C C C C G - G G G G G C T G G A A A G G C 193

ch_PPARG prom 3 G G A G C G C G C A G C C T G G A C C C C C A G C C G C A C C C C G T G G G G G C T G G A A A G G C 194

rh_PPARG prom 3 G G A G C G C G C A G C C T G G A C C C C C A G C C G C A C C G C G - G G G G G C T G G A A A A G C 187

mo_Pparg prom 3 C A C G G A G G C G A T T T G G C C C A C G G C CC C C - - - T G C C C G G G G C T C A C C A G G T 186

ra_Pparg prom 3 C G T C T A A G C A A C T T G G C C C G G G G C T C C C G CCC G C C C G G G G C T C G C C A G G T 190

hu_PPARG prom 3 G A A G T C G C T G C T T T G T G G G C T C C T G C A A G T G C C A G G C G C T G A C C A C T C C T 243

ch_PPARG prom 3 G A A G T C G C T G C T T T G T G G G C T C C T G C A C G T G C C A G G C G C T G A C C A C T C C T 244

rh_PPARG prom 3 G A A G T C G C T G C G T T G T G G G C T C C T G C A C G T G C C A G G C G C T G A C C A C T C C T 237

mo_Pparg prom 3 G T G A G G A A A G C G G G G T C A - C T G T C G C C A A G G C C C C G C C C C G C C A G T G C C C 235

ra_Pparg prom 3 G T G A G G A A A A T G G G G T C A - C T G T C G C C A A G G C C C C G C C C C A C C A G T G C C C 239

hu_PPARG prom 3 C C T G G G A G C C T A A C T G A G G G G G G T A G A G G C A G C A G A G G T T A A C A G A A A T C 293

ch_PPARG prom 3 C C T G G G A G C C T A A C T G A G G G G G G T A G A G G C A G C A G A G G T T A A C A G A A A T C 294

rh_PPARG prom 3 C T T G G G A G C C T A A C T G A G G G G G G T A G A G G C A G C A G A A G T T A A C A G A A A T C 287

mo_Pparg prom 3 C T C T T C A A T C T A A G C A G G G G G C G A G C A C A G G G C C C G G C T C A C G G G A G T A G 285

ra_Pparg prom 3 C T C T T C A G C C T A G G A A G G G G G C G A G C A C A G G G C A G G G C T A A C T G G A G T A G 289

hu_PPARG prom 3 T C A G G T C C C T - - - - - - T G G T G G A A GG T G G G T G T G T A G T C G T - G G T A C T T T 336

ch_PPARG prom 3 T C A G G T C C C T - - - - - - T G G T G G A A GG T G G G T G T G T A G T C G T - G G T A C T T T 337

rh_PPARG prom 3 T C A G G T C C C T C G T T G T T G G T G G A A GG T G G G T G T G T A G T C G T - G G T A C T T T 336

mo_Pparg prom 3 G C A G C C C T C G T G C T G G G G G C G G A A GG T G G G T G T G T G G C T C C C G G T G C T T T 335

ra_Pparg prom 3 G C A G C C C T C G T G G T G G G G G T G G A A GG T G G G T G T G T G G C T C C - G G T G C T T T 338

hu_PPARG prom 3 A C G C C T C G G T G T T T A G G G A G G A G C C T A A G G T AA G G A G T C A G A A A C G G G G A 386

ch_PPARG prom 3 A C G C C T C G G T G T T T A G G G A G G A G C C T A A G G T AA G G A G T C A G A A A C G G G G A 387

rh_PPARG prom 3 A C G C C T C G G T G T T T A G G G A G G A G C T T A A G G T AA G G A G T C A G A A A C G G G G A 386

mo_Pparg prom 3 A T G G C T T G G - G A T T G G G G A G G A G C C T A A G G T G A G G A G G C A G A A A C T G G G A 384

ra_Pparg prom 3 A T G G C T T G G - G A G T G G G G A G G A G C C T A A G G T G A G G A G G C A G A A A C T G G G A 387

hu_PPARG prom 3 G T A A C C G A G C T G C G G C T T T T A T A T A A G G T C A G T G - G T A G G T A A G G A A G G G 435

ch_PPARG prom 3 G T A A C C G A G C T G C G G C T T T T A T A T A A G G T C A G T G - G T A G G T A A G G A A G G G 436

rh_PPARG prom 3 G T A A C C G A G C T G C G G C T T T T A T A T A A G G T C A G T G - G T A G G T A A G G A A G G G 435

mo_Pparg prom 3 G T A G C C T G G - - G C T G C T T T T A T A T A A G G G A C G C G A G G A G G T C A A G A A G G G 432

ra_Pparg prom 3 G T A G C C T G G - - G C T G C T T T T A T A T A A G G G A C T C G A G G A G G T C A A G A A G G G 435

hu_PPARG prom 3 G C C T T A A C C T C T G C T G G T G A C C A G A A G C C T G C A T T T C T G C A T T C T G C T T A 485

ch_PPARG prom 3 G C C T T T A C C T C C G C T G G T G A C C A G A A G G C T G C A T T T C T G C A T T C T G C T T A 486

rh_PPARG prom 3 G C C T T T A C C T C T G C T G G T G A C A A G A A G G C T G C A T T T C T G C A T T C T G C T T A 485

mo_Pparg prom 3 G C C T G G A C C T C T G C T G G G G A T C T G A A G G C T G C A G C G C T A A A T T C T T C T T A 482

ra_Pparg prom 3 G C C T G G A C C T C T G C T G G T G A T C A G A A G G C T G C A G C G C T A A A T T C A T C T T A 485

hu_PPARG prom 3 A T T C C C T T T C C T T A G 500

ch_PPARG prom 3 A T T C C C T T T C C T T A G 501

rh_PPARG prom 3 A T T C C C T T T C C T T A G 500

mo_Pparg prom 3 A C T C C C A T T G A G T A G 497

ra_Pparg prom 3 A C T C C C A T T G A G T A G 500

RREB1 site B

RREB1 site A

C/EBP beta/delta

Sp1

AP-1

deltaEF1/TCF8


Supplementary figure 3a

AP-1 Consensus (+): NTGASTCAG

PPARG prom 3 sequence: AGGAGTCAG

i

C/EBP beta consensus (+): TKDNGMAAK

PPARG prom 3 sequence: TGGTGGAAG

ii

Sp1 Consensus (+): GRGGCRGGGW

PPARG prom 3 sequence: GAAGGTGGGT

iii

deltaEF1 (TCF8) consensus (-): C ACCTTAG

PPARG prom 3 sequence: T/C ACCTTAG

iv

RREB-1 consensus sequence: CCCCAAAC A/C A/C CCCC

PPARG prom 3 site (A) (+): CCCCAGCCGCACCC

PPARG prom 3 site (B) (-): CCCCAGCCCCTCCG

v

Supplementary Figure 3B


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