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BioForum

BioForum. Genomics: Insights and Impacts . Speakers Dr . Jeff Boore - Genome Project Solutions Dr . Katherine Pollard - Gladstone Institute, UCSF Dr . Jonathan Eisen – Genome Center, UCD Dr . Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF Host

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BioForum

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  1. BioForum Genomics: Insights and Impacts Speakers Dr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSF Dr. Jonathan Eisen – Genome Center, UCD Dr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF Host Dr. Brian Simison – California Academy of Sciences

  2. BioForum – Genomics 9:00-9:30 Welcome and Introduction - Brian Simison 9:30-10:20 Dr. Jeff Boore - Genomics:  Where have we come and where are we going? 10:20-10:40 Break 10:40-11:30Dr. Katherine Pollard - What makes us Human? 11:30-12:20 Dr. Jonathan Eisen - Evolution of microbes and their genomes: a phylogenomic perspective 12:20-1:20Lunch 1:20-2:10 Dr. NadavAhituv - Future Genomics 2:10-3:00 Panel Question & Answer Session

  3. Cycle Sequencing - Fred Sanger 1975 – developed chain termination method for DNA sequencing. – Sequenced first complete genome (bacterial phage) 1955 – determined amino acid sequence of Insulin 2 Nobel awards!!

  4. Center for Comparative Genomics Standard DNA sequencing Population genetic studies Whole genome shotgun sequencing ABI 3130xl - 16-capillary sequencer AmershamMegabace 4500 - 384-capillary sequencer

  5. Center for Comparative Genomics PhyloCluster 136-core Apple XserveHigh Performance Computing Cluster Interactive web interface Computer Lab 4 powerful desktops (two 8-core Macs & two 4-core PCs)

  6. Center for Comparative Genomics CryoCollection cDNA libraries, Genomic DNA, BAC libraries, etc 2-d barcoded -80º collection Dynamically linked to tissue and specimen collections

  7. Center for Comparative Genomics Genomics research Jack Dumbacher – Evolution of Bird Viruses David Mindell – mitochondrial genomics & phylogenomics of bird viruses Brian Simison – evolution and origin of Mitochondrial genomes (mechanisms of gene order change).

  8. Role of Genomics at California Academy of Sciences? The field of genomics is not only informing us about ourselves, but it is helping to better understand the living world around us so we can make informed decisions on how to protect that living world

  9. Dr Jeff Boore • B.S. - Penn State • Ph.D. - University of Michigan • NIH Postdoctoral Fellow – University of Minnesota • Visiting Researcher – University of Michigan • Head of Evolutionary Genomics at JGI • Adjunct Professor – UC Berkeley • Owner and CEO – Genome Project Solutions

  10. Dr.JeffBoore Lt. Colonel Jeff Boore 1980 to 2000 – served in US Navy & Air National Guard as a Naval Officer Attended Navy Flight School

  11. Dr. Lt. Colonel Jeff Boore Genomics:  Where have we come and where are we going?

  12. BioForum Genomics: Insights and Impacts Speakers Dr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSF Dr. Jonathan Eisen – Genome Center, UCD Dr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF Moderator Dr. Brian Simison – California Academy of Sciences

  13. Dr Katie Pollard • B.A. – Pomona College, CA - Anthropology & Mathematics • Watson Fellow – socio-political aspects of SIDS in New Zealand, Indonesia & Australia • Ph.D. – UC Berkeley – Biostatistics • Postdoctoral Fellow – UC Berkeley • Postdoctoral Fellow – UC Santa Cruz – Chimpanzee Genome project • Professor – UC Davis Genome Center & Dept. of Statistics • Professor & Investigator – UC Gladstone Institute & Div. of Biostatistics, UCSF

  14. Dr Katie Pollard What makes us Human?

  15. BioForum Genomics: Insights and Impacts Speakers Dr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSF Dr. Jonathan Eisen – Genome Center, UCD Dr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF Moderator Dr. Brian Simison – California Academy of Sciences

  16. Dr Jonathan Eisen • B.S. – Harvard • Ph.D. – Stanford – Evolution of DNA repair processes • Faculty – The Institute for Genomic Research (TIGR) • Professor – UC Davis Genome Center & Dept. of Medical Microbiology & Immunology, School of Medicine • Adjunct appt – Joint Genome Institute • Editor in Chief – PLoS Biology – an open access journal “… making the world’s scientific and medical literature a freely available public resource” • Phylogenomics and the Origin of Novelty in microorganisms

  17. Dr Jonathan Eisen Evolution of microbes and their genomes: A phylogenomic perspective

  18. BioForum Genomics: Insights and Impacts Speakers Dr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSF Dr. Jonathan Eisen – Genome Center, UCD Dr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF Moderator Dr. Brian Simison – California Academy of Sciences

  19. Dr Nadav Ahituv • B.S. – Tel-Aviv University – General Biology • Ph.D. – Tel-Aviv University - Human Genetics • Postdoctoral Fellow – Lawrence Berkeley National Labs - Genomics • Professor – UC San Francisco - Bioengineering and Therapeutic Sciences, Institute for Human Genetics & Department of Biopharmaceutical Sciences – determining the pharmacogenetics of membrane transport proteins that play a role in drug response pathways

  20. Dr Nadav Ahituv Future Genomics

  21. BioForum Genomics: Insights and Impacts Speakers Dr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSF Dr. Jonathan Eisen – Genome Center, UCD Dr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF Moderator Dr. Brian Simison – California Academy of Sciences

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