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Chapter 2 cont’

Chapter 2 cont’. Dr. C. Pemberton. Neuron. Action Potential. Action Potential. ACh = Acetylcholine E = Acetylcholinesterase ACh is released at the axon terminal. ACh crosses the synaptic cleft. ACh binds with a receptor on the post-synaptic membrane. AChE (E) stops the action of ACh.

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Chapter 2 cont’

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  1. Chapter 2 cont’ Dr. C. Pemberton

  2. Neuron

  3. Action Potential

  4. Action Potential

  5. ACh = AcetylcholineE = Acetylcholinesterase ACh is released at the axon terminal. ACh crosses the synaptic cleft. ACh binds with a receptor on the post-synaptic membrane. AChE (E) stops the action of ACh. Normal Transmission of Acetylcholine

  6. ACh is released at the axon terminal. ACh crosses the synaptic cleft. ACh binds with a receptor on the post-synaptic membrane. Nerve agents (NA) block the ability of AChE to stop the action of ACh. ACh continues to work and more ACh builds up in the synapse. ACh = Acetylcholine E = Acetylcholinesterase NA = Nerve Agent Transmission with Nerve Agent Poisoning

  7. ACh is released at the axon terminal. ACh crosses the synaptic cleft. ACh binds with a receptor on the post-synaptic membrane. Nerve agents (NA) block the ability of AChE to stop the action of ACh. Atropine blocks the receptor so that ACh cannot work. Note that there is NO direct effect on the nerve agent or AChE. ACh = Acetylcholine E = Acetylcholinesterase Effect of Atropine on the Transmission of Acetylcholine in the presence of a nerve agent

  8. Discussion • Under what circumstances (if any) do you think psychosurgery or electrical stimulation of peoples’ brains might be warranted? Should those with a chronic history of criminal offense be treated with psychosurgery or electrical brain stimulation? What do you think of psychosurgery or brain stimulations as an alternative to the death penalty.

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