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The Synapse: Part II. 29 February 2012. Housekeeping. Article set 2 available later today Problem set 2 available Friday; due next Friday. Point-Gathering Opportunity!. Take Out Your Clickers!. Which of the following myelinates axons in the PNS?. Schwann cells Oligodendrocytes

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The synapse part ii

The Synapse: Part II

29 February 2012


Housekeeping
Housekeeping

Article set 2 available later today

Problem set 2 available Friday; due next Friday


Point gathering opportunity
Point-Gathering Opportunity!

  • Take Out Your Clickers!


Which of the following myelinates axons in the pns
Which of the following myelinates axons in the PNS?

  • Schwann cells

  • Oligodendrocytes

  • Myelinocytes

  • Phagocytes

  • Erythrocytes


Which of the following is a consequence of myelination
Which of the following is a consequence of myelination?

  • Increased membrane resistance

  • Increased length constant (l)

  • Decreased time constant (t)

  • Faster conduction

  • All of the above


Which of these fibers conducts action potentials fastest
Which of these fibers conducts action potentials fastest?

  • Small diameter, unmyelinated axon

  • Large diameter, unmyelinated axon

  • Small diameter, myelinated axon

  • Large diameter, myelinated axon

  • All of the above conduct at the same rate (“all or none”)


Which of the following happens first
Which of the following happens first?

  • Voltage-gated Ca2+ channels open

  • Neurotransmitter is released into the synapse

  • Action potential arrives at nerve terminal

  • Vesicle membrane is recycled

  • Neurotransmitter vesicle is docked


At this point in the semester i am learning
At this point in the semester, I am learning:

  • Everything

  • Almost everything

  • A lot, but missing much

  • Not very much

  • Nothing


For me the pace of the class is
For me, the pace of the class is:

  • Way too slow

  • A little too slow

  • Just right

  • A little too fast

  • Way too fast


The exam
The Exam

Mean = 119 (83%) Median = 116 Mode = 116

Min = 87 Max = 144



Rectification at the gap junction
Rectification at the Gap Junction


What happens at the chemical synapse

3

2

What happens at the Chemical Synapse

1. NT produced and packaged

2. Vesicle “docked”

3. Action potential arrives

4. Voltage-gated Ca2+ channels open

5. Vesicle fuses with membrane

6. NT released into synapse

7. NT binds to postsynaptic receptors

8. Postsynaptic ion channels open, allowing ions into cell

9. Ion flow changes Vm: “Postsynaptic Potential”


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