The synapse part ii
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The Synapse: Part II. 29 February 2012. Housekeeping. Article set 2 available later today Problem set 2 available Friday; due next Friday. Point-Gathering Opportunity!. Take Out Your Clickers!. Which of the following myelinates axons in the PNS?. Schwann cells Oligodendrocytes

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The Synapse: Part II

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The synapse part ii

The Synapse: Part II

29 February 2012


Housekeeping

Housekeeping

Article set 2 available later today

Problem set 2 available Friday; due next Friday


Point gathering opportunity

Point-Gathering Opportunity!

  • Take Out Your Clickers!


Which of the following myelinates axons in the pns

Which of the following myelinates axons in the PNS?

  • Schwann cells

  • Oligodendrocytes

  • Myelinocytes

  • Phagocytes

  • Erythrocytes


Which of the following is a consequence of myelination

Which of the following is a consequence of myelination?

  • Increased membrane resistance

  • Increased length constant (l)

  • Decreased time constant (t)

  • Faster conduction

  • All of the above


Which of these fibers conducts action potentials fastest

Which of these fibers conducts action potentials fastest?

  • Small diameter, unmyelinated axon

  • Large diameter, unmyelinated axon

  • Small diameter, myelinated axon

  • Large diameter, myelinated axon

  • All of the above conduct at the same rate (“all or none”)


Which of the following happens first

Which of the following happens first?

  • Voltage-gated Ca2+ channels open

  • Neurotransmitter is released into the synapse

  • Action potential arrives at nerve terminal

  • Vesicle membrane is recycled

  • Neurotransmitter vesicle is docked


At this point in the semester i am learning

At this point in the semester, I am learning:

  • Everything

  • Almost everything

  • A lot, but missing much

  • Not very much

  • Nothing


For me the pace of the class is

For me, the pace of the class is:

  • Way too slow

  • A little too slow

  • Just right

  • A little too fast

  • Way too fast


The exam

The Exam

Mean = 119 (83%) Median = 116 Mode = 116

Min = 87 Max = 144


Synapses

Synapses


Rectification at the gap junction

Rectification at the Gap Junction


What happens at the chemical synapse

3

2

What happens at the Chemical Synapse

1. NT produced and packaged

2. Vesicle “docked”

3. Action potential arrives

4. Voltage-gated Ca2+ channels open

5. Vesicle fuses with membrane

6. NT released into synapse

7. NT binds to postsynaptic receptors

8. Postsynaptic ion channels open, allowing ions into cell

9. Ion flow changes Vm: “Postsynaptic Potential”


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