Achondroplasia. Kelly Correia and Alyssa Antonucci January 28, 2010 Hour 3. Achondroplasia is…. A genetic condition Results in abnormally short stature -> Otherwise known as ‘Dwarfism.’ has to do with the bones and how they make bone instead of cartilage. What are some symptoms?.
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Kelly Correia and Alyssa Antonucci
January 28, 2010
What are some symptoms?
Did you know…
Punnett Square 1:
Punnett Square 2:
Punnett Square 3:
Punnett Square 4:
Homozygous Dominant: 25 %
Heterozygous Dominant: 50 %
Homozygous Recessive: 25 %
There are four different possibilities. When getting percentage the total has to be 100%. This means that each box represents 25% since 100 divided by 4 is 25.
Homozygous Dominant :1 GG
Heterozygous Dominant: 2 Ff
Homozygous Recessive: 1 ff
There has to be a total of four combinations in the Punnet Square. There has to be four because that’s the number of possibilities a punnet square can have.
The uppercase F represents the dominant allele. While the lowercase f represents the recessive allele. This is a dominant disorder so even if there is a recessive allele as long as it has another dominant allele , it will remain dominant.
FF= Dominant allele
Ff= Dominant Allele ( with a recessive allele)
ff= Recessive allele
FF: Homozygous dominant
Ff: Heterozygous dominant
ff: Homozygous recessive
Punnet Square Example
Ratio: 3 dominant genes (1 homozygous dominant, 2 heterozygous dominant) , 1 recessive gene (homozygous)
Percentage: 75% dominant (25% homozygous dominant, 50% heterozygous dominant) , 25% recessive (homozygous)
Ratio: 1 FF, 2 Ff, 1 ff
Percentage: 25% FF, 50 % Ff, 25% ff
Ratio: 2 FF, 2 Ff
Percentages: 50% FF, 50% Ff
Ratio: 2 homozygous dominant, 2 heterozygous dominant
Percentages: 50% homozygous dominant, 50% heterozygous dominant
3 Generation Pedigree
White= (homozygous recessive) The person doesn’t have any of the bad genes.
Half-Blue=The person has 1 bad gene and 1 healthy gene
Full blue- (homozygous dominate) The person has both bad genes
Light Orange= (homozygous recessive) The person doesn’t have any of the bad genes.
Half-Light Half- Dark Orange=The person has 1 bad gene and 1 healthy gene
Dark Orange= (homozygous dominate) The person has both bad genes
1.) If the father has both of the bad gene’s and the mother doesn’t have any bad gene’s, how likely will the offspring to be born without any bad genes?
2.) One parent has 1 bad gene and the other parent has one both bad genes of the achondroplasia gene, how likely is the chance of the offspring to have achondroplasia?
3.) If two parents have achondroplasia, how likely is their child to not have achondroplasia?